LOCUS       SIU01615.1               210 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE
            CONSERVED INTEGRAL MEMBRANE PROTEIN protein.
ACCESSION   LT708304-3029
PROTEIN_ID  SIU01615.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB2992C"
                     /note="Mb2992c, -, len: 210 aa. Equivalent to Rv2968c,
                     len: 210 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 210 aa overlap). Probable conserved
                     integral membrane protein, equivalent to O69464 PUTATIVE
                     INTEGRAL MEMBRANE PROTEIN from Mycobacterium leprae (214
                     aa), FASTA scores: opt: 1060, E(): 1.4e-58, (71.95%
                     identity in 214 aa overlap). Also highly similar to others
                     e.g. Q9F844 HYPOTHETICAL INTEGRAL MEMBRANE PROTEIN from
                     Mycobacterium smegmatis (187 aa), FASTA scores: opt: 883,
                     E(): 1.2e-47, (62.8% identity in 190 aa overlap); Q9KXP3
                     PUTATIVE INTEGRAL MEMBRANE PROTEIN from Streptomyces
                     coelicolor (240 aa), FASTA scores: opt: 503, E(): 4.6e-24,
                     (38.0% identity in 192 aa overlap); etc. Mb2992c found to
                     be expressed during exponential growth in Sauton's minimal
                     media by RNA-sequencing."
                     /db_xref="GOA:A0A1R3Y4P3"
                     /db_xref="InterPro:IPR012932"
                     /db_xref="InterPro:IPR038354"
                     /db_xref="InterPro:IPR041714"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3Y4P3"
BEGIN
        1 MVAARPAERS GDPAAVRVPV PSAWWVLIGG VIGLFASMTL TVEKVRILLD PIYVPSCNVN
       61 PIVSCGSVMT TPQASLLGFP NPLLGIAGFT VVVVTGVLAV AKVPLPRWYW IGLAVGILVG
      121 VAFVHWLIFQ SLYRIGALCP YCMVVWAVIA TLLVVVASIV FGPMRENRGS QERVGARLLY
      181 QWRWSLATLW FTTVFLLIMV RFWDYWSTLI
//