LOCUS SIU01615.1 210 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE CONSERVED INTEGRAL MEMBRANE PROTEIN protein. ACCESSION LT708304-3029 PROTEIN_ID SIU01615.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /locus_tag="BQ2027_MB2992C" /note="Mb2992c, -, len: 210 aa. Equivalent to Rv2968c, len: 210 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 210 aa overlap). Probable conserved integral membrane protein, equivalent to O69464 PUTATIVE INTEGRAL MEMBRANE PROTEIN from Mycobacterium leprae (214 aa), FASTA scores: opt: 1060, E(): 1.4e-58, (71.95% identity in 214 aa overlap). Also highly similar to others e.g. Q9F844 HYPOTHETICAL INTEGRAL MEMBRANE PROTEIN from Mycobacterium smegmatis (187 aa), FASTA scores: opt: 883, E(): 1.2e-47, (62.8% identity in 190 aa overlap); Q9KXP3 PUTATIVE INTEGRAL MEMBRANE PROTEIN from Streptomyces coelicolor (240 aa), FASTA scores: opt: 503, E(): 4.6e-24, (38.0% identity in 192 aa overlap); etc. Mb2992c found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="GOA:A0A1R3Y4P3" /db_xref="InterPro:IPR012932" /db_xref="InterPro:IPR038354" /db_xref="InterPro:IPR041714" /db_xref="UniProtKB/TrEMBL:A0A1R3Y4P3" BEGIN 1 MVAARPAERS GDPAAVRVPV PSAWWVLIGG VIGLFASMTL TVEKVRILLD PIYVPSCNVN 61 PIVSCGSVMT TPQASLLGFP NPLLGIAGFT VVVVTGVLAV AKVPLPRWYW IGLAVGILVG 121 VAFVHWLIFQ SLYRIGALCP YCMVVWAVIA TLLVVVASIV FGPMRENRGS QERVGARLLY 181 QWRWSLATLW FTTVFLLIMV RFWDYWSTLI //