LOCUS       SIU01595.1               199 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 chorismate
            pyruvate lyase protein.
ACCESSION   LT708304-3009
PROTEIN_ID  SIU01595.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB2973C"
                     /note="Mb2973c, -, len: 199 aa. Equivalent to Rv2949c,
                     len: 199 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 199 aa overlap). Conserved
                     hypothetical protein, equivalent to Q9CD83|ML0133
                     HYPOTHETICAL PROTEIN from Mycobacterium leprae (210 aa),
                     FASTA scores: opt: 797, E(): 7.4e-47, (62.55% identity in
                     195 aa overlap). Equivalent to AAK47348 from Mycobacterium
                     tuberculosis strain CDC1551 (212 aa) but shorter 13 aa.
                     Protein product from Mb2973c detected using shotgun mass
                     spectrometry and SWATH mass spectrometry. Mb2973c found to
                     be expressed during exponential growth in Sauton's minimal
                     media by RNA-sequencing (TPM > 20)."
                     /db_xref="GOA:Q7TXK6"
                     /db_xref="InterPro:IPR002800"
                     /db_xref="InterPro:IPR028978"
                     /db_xref="UniProtKB/Swiss-Prot:Q7TXK6"
                     /experiment="experimental evidence, no additional details
                     recorded"
BEGIN
        1 MTECFLSDQE IRKLNRDLRI LIAANGTLTR VLNIVADDEV IVQIVKQRIH DVSPKLSEFE
       61 QLGQVGVGRV LQRYIILKGR NSEHLFVAAE SLIAIDRLPA AIITRLTQTN DPLGEVMAAS
      121 HIETFKEEAK VWVGDLPGWL ALHGYQNSRK RAVARRYRVI SGGQPIMVVT EHFLRSVFRD
      181 APHEEPDRWQ FSNAITLAR
//