LOCUS       SIU01594.1               705 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 p-hydroxybenzoyl-
            amp ligase fadd22 protein.
ACCESSION   LT708304-3008
PROTEIN_ID  SIU01594.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="fadD22"
                     /locus_tag="BQ2027_MB2972C"
                     /note="Mb2972c, fadD22, len: 705 aa. Equivalent to
                     Rv2948c, len: 705 aa, from Mycobacterium tuberculosis
                     strain H37Rv, (100.0% identity in 705 aa overlap).
                     Probable fadD22, fatty-acid-CoA synthetase (EC 6.2.1.-).
                     Highly similar to many e.g. Q9CD82|ML0134 putative
                     acyl-CoA synthetase from Mycobacterium leprae (707 aa),
                     fasta scores: opt: 3554, E(): 6.4e-209, (75.9% identity in
                     705 aa overlap). Almost identical to G560509|Q50468
                     PKS002A protein from Mycobacterium tuberculosis (705 aa),
                     fasta scores: opt: 4647, E(): 0, (99.7% identity in 705 aa
                     overlap). Protein product from Mb2972c detected using
                     shotgun mass spectrometry and SWATH mass spectrometry.
                     Mb2972c found to be expressed during exponential growth in
                     Sauton's minimal media by RNA-sequencing."
                     /db_xref="GOA:Q7TXK7"
                     /db_xref="InterPro:IPR000873"
                     /db_xref="InterPro:IPR009081"
                     /db_xref="InterPro:IPR020806"
                     /db_xref="InterPro:IPR025110"
                     /db_xref="InterPro:IPR036736"
                     /db_xref="InterPro:IPR042099"
                     /db_xref="UniProtKB/Swiss-Prot:Q7TXK7"
                     /experiment="experimental evidence, no additional details
                     recorded"
BEGIN
        1 MRNGNLAGLL AEQASEAGWY DRPAFYAADV VTHGQIHDGA ARLGEVLRNR GLSSGDRVLL
       61 CLPDSPDLVQ LLLACLARGV MAFLANPELH RDDHALAARN TEPALVVTSD ALRDRFQPSR
      121 VAEAAELMSE AARVAPGGYE PMGGDALAYA TYTSGTTGPP KAAIHRHADP LTFVDAMCRK
      181 ALRLTPEDTG LCSARMYFAY GLGNSVWFPL ATGGSAVINS APVTPEAAAI LSARFGPSVL
      241 YGVPNFFARV IDSCSPDSFR SLRCVVSAGE ALELGLAERL MEFFGGIPIL DGIGSTEVGQ
      301 TFVSNRVDEW RLGTLGRVLP PYEIRVVAPD GTTAGPGVEG DLWVRGPAIA KGYWNRPDSP
      361 VANEGWLDTR DRVCIDSDGW VTYRCRADDT EVIGGVNVDP REVERLIIED EAVAEAAVVA
      421 VRESTGASTL QAFLVATSGA TIDGSVMRDL HRGLLNRLSA FKVPHRFAVV DRLPRTPNGK
      481 LVRGALRKQS PTKPIWELSL TEPGSGVRAQ RDDLSASNMT IAGGNDGGAT LRERLVALRQ
      541 ERQRLVVDAV CAEAAKMLGE PDPWSVDQDL AFSELGFDSQ MTVTLCKRLA AVTGLRLPET
      601 VGWDYGSISG LAQYLEAELA GGHGRLKSAG PVNSGATGLW AIEEQLNKVE ELVAVIADGE
      661 KQRVADRLRA LLGTIAGSEA GLGKLIQAAS TPDEIFQLID SELGK
//