LOCUS       SIU01591.1               233 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE
            CONSERVED LIPOPROTEIN LPPX protein.
ACCESSION   LT708304-3005
PROTEIN_ID  SIU01591.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="lppX"
                     /locus_tag="BQ2027_MB2970C"
                     /note="Mb2970c, lppX, len: 233 aa. Equivalent to Rv2945c,
                     len: 233 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 233 aa overlap). Probable lppX,
                     conserved lipoprotein, equivalent to Q9CD80 PUTATIVE
                     LIPOPROTEIN from Mycobacterium leprae (233 aa), FASTA
                     scores: opt: 1165, E(): 2.1e-65, (76.4% identity in 233 aa
                     overlap); and similar to Q9CCP6|ML0557 from Mycobacterium
                     leprae (238 aa), FASTA scores: opt: 338, E(): 7.4e-14,
                     (30.75% identity in 231 aa overlap). Also similar to
                     others from Mycobacterium tuberculosis e.g.
                     P71679|LPRG_MYCTU LIPOPROTEIN (236 aa), FASTA scores: opt:
                     342, E(): 4.1e-14, (32.05% identity in 231 aa overlap);
                     etc. Contains PS00013 Prokaryotic membrane lipoprotein
                     lipid attachment site, and has in its N-terminal a signal
                     peptide. BELONGS TO THE LPPX/LPRAFG FAMILY OF
                     LIPOPROTEINS. Protein product from Mb2970c detected using
                     shotgun mass spectrometry and SWATH mass spectrometry.
                     Mb2970c found to be expressed during exponential growth in
                     Sauton's minimal media by RNA-sequencing."
                     /db_xref="GOA:P65307"
                     /db_xref="InterPro:IPR009830"
                     /db_xref="InterPro:IPR029046"
                     /db_xref="UniProtKB/Swiss-Prot:P65307"
                     /experiment="experimental evidence, no additional details
                     recorded"
BEGIN
        1 MNDGKRAVTS AVLVVLGACL ALWLSGCSSP KPDAEEQGVP VSPTASDPAL LAEIRQSLDA
       61 TKGLTSVHVA VRTTGKVDSL LGITSADVDV RANPLAAKGV CTYNDEQGVP FRVQGDNISV
      121 KLFDDWSNLG SISELSTSRV LDPAAGVTQL LSGVTNLQAQ GTEVIDGIST TKITGTIPAS
      181 SVKMLDPGAK SARPATVWIA QDGSHHLVRA SIDLGSGSIQ LTQSKWNEPV NVD
//