LOCUS SIU01573.1 245 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 FIG00814129: Possible chaperone protein. ACCESSION LT708304-2987 PROTEIN_ID SIU01573.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /locus_tag="BQ2027_MB2952C" /note="Mb2952c, -, len: 245 aa. Equivalent to Rv2927c, len: 245 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 245 aa overlap). Conserved hypothetical protein, equivalent to Q9CBS6|ML1661|MLCB1243.13 (alias O69467) HYPOTHETICAL PROTEIN from Mycobacterium leprae (247 aa), FASTA scores: opt: 1440, E(): 4.9e-76, (90.6% identity in 245 aa overlap). Also similar to many hypothetical proteins from other organisms e.g. Q9ZBR0|SC7A1.13 HYPOTHETICAL 41.0 KDA PROTEIN from Streptomyces coelicolor (379 aa), FASTA scores: opt: 266, E(): 3.4e-08, (29.9% identity in 234 aa overlap); etc. Also some similarity with P46815|AG84_MYCLE|ML0922 ANTIGEN 84 from Mycobacterium leprae (266 aa), FASTA scores: opt: 193, E(): 0.00043, (28.7% identity in 136 aa overlap) (see citation below); and P46816|AG84_MYCTU|WAG31|Rv2145c|MT2204|MTCY270.23 ANTIGEN 84 from Mycobacterium tuberculosis (260 aa), FASTA scores: opt: 178, E(): 0.0031, (34.35% identity in 131 aa overlap) (see citation below). Contains potential coiled-coil region. Protein product from Mb2952c detected using shotgun mass spectrometry and SWATH mass spectrometry. Mb2952c found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="UniProtKB/Swiss-Prot:P65060" BEGIN 1 MYRVFEALDE LSAIVEEARG VPMTAGCVVP RGDVLELIDD IKDAIPGELD DAQDVLDARD 61 SMLQDAKTHA DSMVSSATTE AESILNHART EADRILSDAK AQADRMVSEA RQHSERMVAD 121 AREEAIRIAT AAKREYEASV SRAQAECDRL IENGNISYEK AVQEGIKEQQ RLVSQNEVVA 181 AANAESTRLV DTAHAEADRL RGECDIYVDN KLAEFEEFLN GTLRSVGRGR HQLRTAAGTH 241 DYAVR //