LOCUS       SIU01573.1               245 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 FIG00814129:
            Possible chaperone protein.
ACCESSION   LT708304-2987
PROTEIN_ID  SIU01573.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB2952C"
                     /note="Mb2952c, -, len: 245 aa. Equivalent to Rv2927c,
                     len: 245 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 245 aa overlap). Conserved
                     hypothetical protein, equivalent to
                     Q9CBS6|ML1661|MLCB1243.13 (alias O69467) HYPOTHETICAL
                     PROTEIN from Mycobacterium leprae (247 aa), FASTA scores:
                     opt: 1440, E(): 4.9e-76, (90.6% identity in 245 aa
                     overlap). Also similar to many hypothetical proteins from
                     other organisms e.g. Q9ZBR0|SC7A1.13 HYPOTHETICAL 41.0 KDA
                     PROTEIN from Streptomyces coelicolor (379 aa), FASTA
                     scores: opt: 266, E(): 3.4e-08, (29.9% identity in 234 aa
                     overlap); etc. Also some similarity with
                     P46815|AG84_MYCLE|ML0922 ANTIGEN 84 from Mycobacterium
                     leprae (266 aa), FASTA scores: opt: 193, E(): 0.00043,
                     (28.7% identity in 136 aa overlap) (see citation below);
                     and P46816|AG84_MYCTU|WAG31|Rv2145c|MT2204|MTCY270.23
                     ANTIGEN 84 from Mycobacterium tuberculosis (260 aa), FASTA
                     scores: opt: 178, E(): 0.0031, (34.35% identity in 131 aa
                     overlap) (see citation below). Contains potential
                     coiled-coil region. Protein product from Mb2952c detected
                     using shotgun mass spectrometry and SWATH mass
                     spectrometry. Mb2952c found to be expressed during
                     exponential growth in Sauton's minimal media by
                     RNA-sequencing."
                     /db_xref="UniProtKB/Swiss-Prot:P65060"
BEGIN
        1 MYRVFEALDE LSAIVEEARG VPMTAGCVVP RGDVLELIDD IKDAIPGELD DAQDVLDARD
       61 SMLQDAKTHA DSMVSSATTE AESILNHART EADRILSDAK AQADRMVSEA RQHSERMVAD
      121 AREEAIRIAT AAKREYEASV SRAQAECDRL IENGNISYEK AVQEGIKEQQ RLVSQNEVVA
      181 AANAESTRLV DTAHAEADRL RGECDIYVDN KLAEFEEFLN GTLRSVGRGR HQLRTAAGTH
      241 DYAVR
//