LOCUS SIU01568.1 93 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE ACYLPHOSPHATASE ACYP (ACYLPHOSPHATE PHOSPHOHYDROLASE) protein. ACCESSION LT708304-2982 PROTEIN_ID SIU01568.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /gene="acyP" /locus_tag="BQ2027_MB2947C" /note="Mb2947c, acyP, len: 93 aa. Equivalent to Rv2922A, len: 93 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 93 aa overlap). Probable acyP, acylphosphatase (acylphosphate phosphohydrolase) (EC 3.6.1.7), highly similar to others e.g. Q9ZBQ3|SC7A1.20 PUTATIVE ACYLPHOSPHATASE from Streptomyces coelicolor (93 aa), FASTA scores: opt: 345, E(): 9.5e-19, (58.9% identity in 90 aa overlap); P75877|ACYP_ECOLI|YCCX|B0968|Z1320|ECS1 052 PUTATIVE ACYLPHOSPHATASE from Escherichia coli strains K12 and O157:H7 (92 aa), FASTA scores: opt: 220, E(): 2e-09, (44.95% identity in 89 aa overlap); Q9RVU3|DR0929 PUTATIVE ACYLPHOSPHATASE from Deinococcus radiodurans (87 aa), FASTA scores: opt: 193, E(): 2.1e-07, (44.3% identity in 79 aa overlap); etc. BELONGS TO THE ACYLPHOSPHATASE FAMILY. Protein product from Mb2947c detected using shotgun mass spectrometry and SWATH mass spectrometry. Mb2947c found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="GOA:P69418" /db_xref="InterPro:IPR001792" /db_xref="InterPro:IPR017968" /db_xref="InterPro:IPR020456" /db_xref="InterPro:IPR036046" /db_xref="UniProtKB/Swiss-Prot:P69418" BEGIN 1 MSAPDVRLTA WVHGWVQGVG FRWWTRCRAL ELGLTGYAAN HADGRVLVVA QGPRAACQKL 61 LQLLQGDTTP GRVAKVVADW SQSTEQITGF SER //