LOCUS       SIU01568.1                93 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE
            ACYLPHOSPHATASE ACYP (ACYLPHOSPHATE PHOSPHOHYDROLASE)
            protein.
ACCESSION   LT708304-2982
PROTEIN_ID  SIU01568.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="acyP"
                     /locus_tag="BQ2027_MB2947C"
                     /note="Mb2947c, acyP, len: 93 aa. Equivalent to Rv2922A,
                     len: 93 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 93 aa overlap). Probable acyP,
                     acylphosphatase (acylphosphate phosphohydrolase) (EC
                     3.6.1.7), highly similar to others e.g. Q9ZBQ3|SC7A1.20
                     PUTATIVE ACYLPHOSPHATASE from Streptomyces coelicolor (93
                     aa), FASTA scores: opt: 345, E(): 9.5e-19, (58.9% identity
                     in 90 aa overlap); P75877|ACYP_ECOLI|YCCX|B0968|Z1320|ECS1
                     052 PUTATIVE ACYLPHOSPHATASE from Escherichia coli strains
                     K12 and O157:H7 (92 aa), FASTA scores: opt: 220, E():
                     2e-09, (44.95% identity in 89 aa overlap); Q9RVU3|DR0929
                     PUTATIVE ACYLPHOSPHATASE from Deinococcus radiodurans (87
                     aa), FASTA scores: opt: 193, E(): 2.1e-07, (44.3% identity
                     in 79 aa overlap); etc. BELONGS TO THE ACYLPHOSPHATASE
                     FAMILY. Protein product from Mb2947c detected using
                     shotgun mass spectrometry and SWATH mass spectrometry.
                     Mb2947c found to be expressed during exponential growth in
                     Sauton's minimal media by RNA-sequencing."
                     /db_xref="GOA:P69418"
                     /db_xref="InterPro:IPR001792"
                     /db_xref="InterPro:IPR017968"
                     /db_xref="InterPro:IPR020456"
                     /db_xref="InterPro:IPR036046"
                     /db_xref="UniProtKB/Swiss-Prot:P69418"
BEGIN
        1 MSAPDVRLTA WVHGWVQGVG FRWWTRCRAL ELGLTGYAAN HADGRVLVVA QGPRAACQKL
       61 LQLLQGDTTP GRVAKVVADW SQSTEQITGF SER
//