LOCUS       SIU01538.1               325 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 POSSIBLE
            OXIDOREDUCTASE protein.
ACCESSION   LT708304-2952
PROTEIN_ID  SIU01538.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB2917"
                     /note="Mb2917, -, len: 325 aa. Equivalent to Rv2893, len:
                     325 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 325 aa overlap). Possible
                     oxidoreductase (EC 1.-.-.-), showing similarity with
                     various proteins and/or oxidoreductases e.g. Q9AE05|RIF11
                     eleventh protein in the rif biosynthetic gene cluster from
                     Amycolatopsis mediterranei (Nocardia mediterranei) (294
                     aa), FASTA scores: opt: 270, E(): 4.8e-10, (34.5% identity
                     in 313 aa overlap); O52567 REDUCTASE from Amycolatopsis
                     mediterranei (Nocardia mediterranei) (153 aa), FASTA
                     scores: opt: 251, E(): 5e-09, (42.4% identity in 125 aa
                     overlap); Q58929|MER|MJ1534 F420-DEPENDENT
                     METHYLENETETRAHYDROMETHANOPTERIN REDUCTASE (EC 1.5.99.-)
                     from Methanococcus jannaschii (331 aa), FASTA scores: opt:
                     249, E(): 1.2e-08, (29.7% identity in 283 aa overlap);
                     etc. Also some similarity with others proteins from
                     Mycobacterium tuberculosis strains H37Rv and CDC1551 e.g.
                     P71844|Rv0791c|MTCY369.35c PUTATIVE OXIDOREDUCTASE (347
                     aa), FASTA scores: opt: 264, E(): 1.3e-09, (29.05%
                     identity in 272 aa overlap); and P96809|Rv0132|MTCI5.06c
                     PUTATIVE OXIDOREDUCTASE (360 aa), FASTA scores: opt: 260,
                     E(): 2.4e-09, (33.05% identity in 239 aa overlap). Protein
                     product from Mb2917 detected using shotgun mass
                     spectrometry and SWATH mass spectrometry."
                     /db_xref="GOA:A0A1R3Y2X5"
                     /db_xref="InterPro:IPR011251"
                     /db_xref="InterPro:IPR019923"
                     /db_xref="InterPro:IPR036661"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3Y2X5"
                     /experiment="experimental evidence, no additional details
                     recorded"
BEGIN
        1 MTVASTAHHT RRLRFGLAAP LPRAGTQMRA FAQAVEAAGF DVLAFPDHLV PSVSPFAGAT
       61 AAAMATQRLH TGTLVLNNDF RHPVDTAREA AGVATLAEGR FELGLGAGHR RSEYDAAGIT
      121 FDSGATRVAR LIESAHLIRA LLDAEPVDFD GQHYRVHAEA GSLVAPPKVR VPLLVGGNGT
      181 EVLRLGGRIA DIVGLAGISH NRDATQVRFT HFDADGLADR IAVVRHAAGD RFEAIELNAL
      241 IQAVVCTNDR NAAAAELAAT LGGITPEQVL ESPFLLLGTH EQMAEALAAR QRRFGVSYWT
      301 VFDEWAGRAS AMRDIAEVIA LLRYG
//