LOCUS       SIU01504.1               308 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 POSSIBLE
            AMIDOTRANSFERASE protein.
ACCESSION   LT708304-2918
PROTEIN_ID  SIU01504.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB2884C"
                     /note="Mb2884c, -, len: 308 aa. Equivalent to Rv2859c,
                     len: 308 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 308 aa overlap). Possible
                     amidotransferase (EC 6.3.5.- or 2.-.-.-), equivalent (but
                     longer 58 aa) to Q9CBU9|ML1573 POSSIBLE AMIDOTRANSFERASE
                     from Mycobacterium leprae (249 aa), FASTA scores: opt:
                     1226, E(): 3e-64, (71.55% identity in 239 aa overlap).
                     Also similar to other amidotransferases and hypothetical
                     proteins, but shorter in N-terminus e.g. O88072|SCI35.37
                     HYPOTHETICAL 25.3 KDA PROTEIN from Streptomyces coelicolor
                     (242 aa), FASTA scores: opt: 683, E(): 1.2e-32, (47.65%
                     identity in 235 aa overlap); AAK79730|Q97I88|CAC1764
                     PREDICTED GLUTAMINE AMIDOTRANSFERASE from Clostridium
                     acetobutylicum (241 aa), FASTA scores: opt: 458, E():
                     1.6e-19, (32.95% identity in 246 aa overlap);
                     AAK75201|Q97QV9|SP1089 GLUTAMINE AMIDOTRANSFERASE CLASS I
                     from Streptococcus pneumoniae (229 aa), FASTA scores: opt:
                     431, E(): 5.6e-18, (34.75% identity in 236 aa overlap);
                     etc. Contains three 17 aa repeats at the N-terminus very
                     similar to those in other Mycobacterium tuberculosis
                     proteins e.g. Q10699|YY30_MYCTU|Rv2090|MT2151|MTCY49.30
                     PUTATIVE 5'-3' EXONUCLEASE RV2090 (EC 3.1.11.-). Protein
                     product from Mb2884c detected using shotgun mass
                     spectrometry and SWATH mass spectrometry. Mb2884c found to
                     be expressed during exponential growth in Sauton's minimal
                     media by RNA-sequencing (TPM > 20)."
                     /db_xref="GOA:A0A1R3Y2F8"
                     /db_xref="InterPro:IPR011697"
                     /db_xref="InterPro:IPR017926"
                     /db_xref="InterPro:IPR029062"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3Y2F8"
BEGIN
        1 MDLSASRSDG GDPLRPASPR LRSPVSDGGD PLRPASPRLR SPVSDGGDPL RPASPRLRSP
       61 LGASRPVVGL TAYLEQVRTG VWDIPAGYLP ADYFEGITMA GGVAVLLPPQ PVDPESVGCV
      121 LDSLHALVIT GGYDLDPAAY GQEPHPATDH PRPGRDAWEF ALLRGALQRG MPVLGICRGT
      181 QVLNVALGGT LHQHLPDILG HSGHRAGNGV FTRLPVHTAS GTRLAELIGE SADVPCYHHQ
      241 AIDQVGEGLV VSAVDVDGVI EALELPGDTF VLAVQWHPEK SLDDLRLFKA LVDAASGYAG
      301 RQSQAEPR
//