LOCUS       SIU01485.1                99 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 COG2740:
            Predicted nucleic-acid-binding protein implicated in transcription
            termination protein.
ACCESSION   LT708304-2899
PROTEIN_ID  SIU01485.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB2865C"
                     /note="Mb2865c, -, len: 99 aa. Equivalent to Rv2840c, len:
                     99 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 99 aa overlap). Conserved hypothetical
                     protein, equivalent to Q9Z5J0|ML1557|MLCB596.13
                     HYPOTHETICAL 11.6 KDA PROTEIN from Mycobacterium leprae
                     (106 aa), FASTA scores: opt: 501, E(): 2.3e-29, (501%
                     identity in 96 aa overlap). Also highly similar to other
                     hypothetical proteins e.g. Q9KYR0|SC5H4.29 from
                     Streptomyces coelicolor (101 aa), FASTA scores: opt: 256,
                     E(): 1.4e-11, (50.6% identity in 81 aa overlap); Q9APM9
                     from Myxococcus xanthus (111 aa), FASTA scores: opt: 174,
                     E(): 1.3e-05, (42.25% identity in 97 aa overlap); and
                     similar to to others e.g. N-terminus of CAC41675|SMC02913
                     from Rhizobium meliloti (Sinorhizobium meliloti) (230 aa),
                     FASTA scores: opt: 172, E(): 3e-05, (42.4% identity in 66
                     aa overlap). Protein product from Mb2865c detected using
                     SWATH mass spectrometry. Mb2865c found to be expressed
                     during exponential growth in Sauton's minimal media by
                     RNA-sequencing."
                     /db_xref="InterPro:IPR007393"
                     /db_xref="InterPro:IPR035931"
                     /db_xref="InterPro:IPR037465"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3Y4A8"
BEGIN
        1 MRTCVGCRKR GLAVELLRVV AVSTGNGNYA VIVDTATSLP GRGAWLHPLR QCAQQAIRRR
       61 AFARALRIAG SPDTSAVVEY LESLGELEPP GNRTGSNRT
//