LOCUS SIU01485.1 99 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 COG2740: Predicted nucleic-acid-binding protein implicated in transcription termination protein. ACCESSION LT708304-2899 PROTEIN_ID SIU01485.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /locus_tag="BQ2027_MB2865C" /note="Mb2865c, -, len: 99 aa. Equivalent to Rv2840c, len: 99 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 99 aa overlap). Conserved hypothetical protein, equivalent to Q9Z5J0|ML1557|MLCB596.13 HYPOTHETICAL 11.6 KDA PROTEIN from Mycobacterium leprae (106 aa), FASTA scores: opt: 501, E(): 2.3e-29, (501% identity in 96 aa overlap). Also highly similar to other hypothetical proteins e.g. Q9KYR0|SC5H4.29 from Streptomyces coelicolor (101 aa), FASTA scores: opt: 256, E(): 1.4e-11, (50.6% identity in 81 aa overlap); Q9APM9 from Myxococcus xanthus (111 aa), FASTA scores: opt: 174, E(): 1.3e-05, (42.25% identity in 97 aa overlap); and similar to to others e.g. N-terminus of CAC41675|SMC02913 from Rhizobium meliloti (Sinorhizobium meliloti) (230 aa), FASTA scores: opt: 172, E(): 3e-05, (42.4% identity in 66 aa overlap). Protein product from Mb2865c detected using SWATH mass spectrometry. Mb2865c found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="InterPro:IPR007393" /db_xref="InterPro:IPR035931" /db_xref="InterPro:IPR037465" /db_xref="UniProtKB/TrEMBL:A0A1R3Y4A8" BEGIN 1 MRTCVGCRKR GLAVELLRVV AVSTGNGNYA VIVDTATSLP GRGAWLHPLR QCAQQAIRRR 61 AFARALRIAG SPDTSAVVEY LESLGELEPP GNRTGSNRT //