LOCUS       SIU01482.1               336 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 Cyclic-
            di-AMP phosphodiesterase MSMEG_2630 protein.
ACCESSION   LT708304-2896
PROTEIN_ID  SIU01482.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="nrnA"
                     /locus_tag="BQ2027_MB2862C"
                     /note="Mb2862c, -, len: 336 aa. Equivalent to Rv2837c,
                     len: 336 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 336 aa overlap). Conserved
                     hypothetical protein, showing some similarity with other
                     proteins e.g. O67552|AQ_1630 HYPOTHETICAL 36.2 KDA PROTEIN
                     from Aquifex aeolicus (325 aa), FASTA scores: opt: 498,
                     E(): 3.6e-25, (32.8% identity in 314 aa overlap);
                     Q9X1T1|TM1595 CONSERVED HYPOTHETICAL PROTEIN from
                     Thermotoga maritima (333 aa), FASTA scores: opt: 482, E():
                     4.1e-24, (34.85% identity in 304 aa overlap);
                     Q9RW43|DR0826 CONSERVED HYPOTHETICAL PROTEIN from
                     Deinococcus radiodurans (338 aa), FASTA scores: opt: 444,
                     E(): 1.3e-21, (33.85% identity in 331 aa overlap); etc.
                     Equivalent to AAK47229 from Mycobacterium tuberculosis
                     strain CDC1551 (316 aa) but longer 20 aa. Protein product
                     from Mb2862c detected using shotgun mass spectrometry and
                     SWATH mass spectrometry. Mb2862c found to be expressed
                     during exponential growth in Sauton's minimal media by
                     RNA-sequencing."
                     /db_xref="GOA:A0A1R3Y2C0"
                     /db_xref="InterPro:IPR001667"
                     /db_xref="InterPro:IPR003156"
                     /db_xref="InterPro:IPR038763"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3Y2C0"
BEGIN
        1 MTTIDPRSEL VDGRRRAGAR VDAVGAAALL SAAARVGVVC HVHPDADTIG AGLALALVLD
       61 GCGKRVEVSF AAPATLPESL RSLPGCHLLV RPEVMRRDVD LVVTVDIPSV DRLGALGDLT
      121 DSGRELLVID HHASNDLFGT ANFIDPSADS TTTMVAEILD AWGKPIDPRV AHCIYAGLAT
      181 DTGSFRWASV RGYRLAARLV EIGVDNATVS RTLMDSHPFT WLPLLSRVLG SAQLVSEAVG
      241 GRGLVYVVVD NREWVAARSE EVESIVDIVR TTQQAEVAAV FKEVEPHRWS VSMRAKTVNL
      301 AAVASGFGGG GHRLAAGYTT TGSIDDAVAS LRAALG
//