LOCUS SIU01482.1 336 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 Cyclic- di-AMP phosphodiesterase MSMEG_2630 protein. ACCESSION LT708304-2896 PROTEIN_ID SIU01482.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /gene="nrnA" /locus_tag="BQ2027_MB2862C" /note="Mb2862c, -, len: 336 aa. Equivalent to Rv2837c, len: 336 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 336 aa overlap). Conserved hypothetical protein, showing some similarity with other proteins e.g. O67552|AQ_1630 HYPOTHETICAL 36.2 KDA PROTEIN from Aquifex aeolicus (325 aa), FASTA scores: opt: 498, E(): 3.6e-25, (32.8% identity in 314 aa overlap); Q9X1T1|TM1595 CONSERVED HYPOTHETICAL PROTEIN from Thermotoga maritima (333 aa), FASTA scores: opt: 482, E(): 4.1e-24, (34.85% identity in 304 aa overlap); Q9RW43|DR0826 CONSERVED HYPOTHETICAL PROTEIN from Deinococcus radiodurans (338 aa), FASTA scores: opt: 444, E(): 1.3e-21, (33.85% identity in 331 aa overlap); etc. Equivalent to AAK47229 from Mycobacterium tuberculosis strain CDC1551 (316 aa) but longer 20 aa. Protein product from Mb2862c detected using shotgun mass spectrometry and SWATH mass spectrometry. Mb2862c found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="GOA:A0A1R3Y2C0" /db_xref="InterPro:IPR001667" /db_xref="InterPro:IPR003156" /db_xref="InterPro:IPR038763" /db_xref="UniProtKB/TrEMBL:A0A1R3Y2C0" BEGIN 1 MTTIDPRSEL VDGRRRAGAR VDAVGAAALL SAAARVGVVC HVHPDADTIG AGLALALVLD 61 GCGKRVEVSF AAPATLPESL RSLPGCHLLV RPEVMRRDVD LVVTVDIPSV DRLGALGDLT 121 DSGRELLVID HHASNDLFGT ANFIDPSADS TTTMVAEILD AWGKPIDPRV AHCIYAGLAT 181 DTGSFRWASV RGYRLAARLV EIGVDNATVS RTLMDSHPFT WLPLLSRVLG SAQLVSEAVG 241 GRGLVYVVVD NREWVAARSE EVESIVDIVR TTQQAEVAAV FKEVEPHRWS VSMRAKTVNL 301 AAVASGFGGG GHRLAAGYTT TGSIDDAVAS LRAALG //