LOCUS       SIU01478.1               275 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE
            Sn-GLYCEROL-3-PHOSPHATE TRANSPORT INTEGRAL MEMBRANE PROTEIN
            ABC TRANSPORTER UGPE protein.
ACCESSION   LT708304-2892
PROTEIN_ID  SIU01478.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="ugpE"
                     /locus_tag="BQ2027_MB2858C"
                     /note="Mb2858c, ugpE, len: 275 aa. Equivalent to Rv2834c,
                     len: 275 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 275 aa overlap). Probable ugpE,
                     Sn-glycerol-3-phosphate transport integral membrane
                     protein ABC transporter (see citation below), similar to
                     various permeases e.g. Q9KDY3|BH1078 GLYCEROL-3-PHOSPHATE
                     ABC TRANSPORTER from Bacillus halodurans (270 aa), FASTA
                     scores: opt: 620, E(): 4.3e-32, (34.7% identity in 268 aa
                     overlap); Q9X0K6|TM1122 GLYCEROL-3-PHOSPHATE ABC
                     TRANSPORTER PERMEASE PROTEIN from Thermotoga maritima (276
                     aa), FASTA scores: opt: 605, E(): 3.9e-31, (32.5% identity
                     in 274 aa overlap); AAG58557|UGPE SN-GLYCEROL 3-PHOSPHATE
                     TRANSPORT SYSTEM (INTEGRAL MEMBRANE PROTEIN) from
                     Escherichia coli strain O157:H7 and EDL933 (281 aa), FASTA
                     scores: opt: 574, E(): 3.7e-29, (32.95% identity in 264 aa
                     overlap); P10906|UGPE_ECOLI|B3451 SN-GLYCEROL-3-PHOSPHATE
                     TRANSPORT SYSTEM PERMEASE PROTEIN from Escherichia coli
                     strain K12 (281 aa), FASTA scores: opt: 569, E(): 7.6e-29,
                     (32.6% identity in 264 aa overlap); etc. Contains PS00402
                     Binding-protein-dependent transport systems inner membrane
                     comp signature."
                     /db_xref="GOA:A0A1R3Y2R8"
                     /db_xref="InterPro:IPR000515"
                     /db_xref="InterPro:IPR035906"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3Y2R8"
BEGIN
        1 MTPDRLRSSV GYAAMLLVVT LIAGPLLFVF FTSFKDQPDI YAQPTSWWPL RWYPQNYRTA
       61 TEQIPFWTFL RNSLIITSVL AVVKFTLGVL SAFGLVFVRF PGRTAVFLVI IAALMVPNQI
      121 TVISNYALIS HLGLRNTFAG IILPLAGVAF GTFLMRNHFL SLPAEIIEAA RMDGARWWQL
      181 LLRVVLPMSR PTMVAVGVIT VVNEWNEYLW PFLMSDDESV APLPIGLTFL QQAEGVTNWG
      241 PVMAVTLLAM LPILLVFIAL QRQMIKGLTS GAVKG
//