LOCUS SIU01478.1 275 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE Sn-GLYCEROL-3-PHOSPHATE TRANSPORT INTEGRAL MEMBRANE PROTEIN ABC TRANSPORTER UGPE protein. ACCESSION LT708304-2892 PROTEIN_ID SIU01478.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /gene="ugpE" /locus_tag="BQ2027_MB2858C" /note="Mb2858c, ugpE, len: 275 aa. Equivalent to Rv2834c, len: 275 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 275 aa overlap). Probable ugpE, Sn-glycerol-3-phosphate transport integral membrane protein ABC transporter (see citation below), similar to various permeases e.g. Q9KDY3|BH1078 GLYCEROL-3-PHOSPHATE ABC TRANSPORTER from Bacillus halodurans (270 aa), FASTA scores: opt: 620, E(): 4.3e-32, (34.7% identity in 268 aa overlap); Q9X0K6|TM1122 GLYCEROL-3-PHOSPHATE ABC TRANSPORTER PERMEASE PROTEIN from Thermotoga maritima (276 aa), FASTA scores: opt: 605, E(): 3.9e-31, (32.5% identity in 274 aa overlap); AAG58557|UGPE SN-GLYCEROL 3-PHOSPHATE TRANSPORT SYSTEM (INTEGRAL MEMBRANE PROTEIN) from Escherichia coli strain O157:H7 and EDL933 (281 aa), FASTA scores: opt: 574, E(): 3.7e-29, (32.95% identity in 264 aa overlap); P10906|UGPE_ECOLI|B3451 SN-GLYCEROL-3-PHOSPHATE TRANSPORT SYSTEM PERMEASE PROTEIN from Escherichia coli strain K12 (281 aa), FASTA scores: opt: 569, E(): 7.6e-29, (32.6% identity in 264 aa overlap); etc. Contains PS00402 Binding-protein-dependent transport systems inner membrane comp signature." /db_xref="GOA:A0A1R3Y2R8" /db_xref="InterPro:IPR000515" /db_xref="InterPro:IPR035906" /db_xref="UniProtKB/TrEMBL:A0A1R3Y2R8" BEGIN 1 MTPDRLRSSV GYAAMLLVVT LIAGPLLFVF FTSFKDQPDI YAQPTSWWPL RWYPQNYRTA 61 TEQIPFWTFL RNSLIITSVL AVVKFTLGVL SAFGLVFVRF PGRTAVFLVI IAALMVPNQI 121 TVISNYALIS HLGLRNTFAG IILPLAGVAF GTFLMRNHFL SLPAEIIEAA RMDGARWWQL 181 LLRVVLPMSR PTMVAVGVIT VVNEWNEYLW PFLMSDDESV APLPIGLTFL QQAEGVTNWG 241 PVMAVTLLAM LPILLVFIAL QRQMIKGLTS GAVKG //