LOCUS SIU01471.1 181 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 CONSERVED HYPOTHETICAL PROTEIN protein. ACCESSION LT708304-2885 PROTEIN_ID SIU01471.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /locus_tag="BQ2027_MB2852C" /note="Mb2852c, -, len: 181 aa. Equivalent to Rv2828c, len: 181 aa, from Mycobacterium tuberculosis strain H37Rv, (99.4% identity in 181 aa overlap). Conserved hypothetical protein, similar to Q9RY53|DR0097 CONSERVED HYPOTHETICAL PROTEIN from Deinococcus radiodurans (189 aa), FASTA scores: opt: 267, E(): 1.9e-11, (34.1% identity in 176 aa overlap); and shows some similarity with N-terminus of O27278|MTH1210 MRR RESTRICTION SYSTEM RELATED PROTEIN from Methanothermobacter thermautotrophicus (340 aa), FASTA scores: opt: 133, E(): 0.07, (28.55% identity in 112 aa overlap). Also equivalent to downstream ORF P71627|Rv2825c|MTCY16B7.17 from Mycobacterium tuberculosis strain H37Rv (alias AAK47217 from strain CDC1551, 246 aa) (215 aa), FASTA scores: opt: 1173, E(): 8.3e-75, (98.9% identity in 181 aa overlap). Mb2852c found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="InterPro:IPR008307" /db_xref="InterPro:IPR014923" /db_xref="UniProtKB/TrEMBL:A0A1R3Y2C7" BEGIN 1 MTPALKEWSA AVHALLDGRQ TVLLRKGGIG EKRFEVAAHE FLLFPTVAHS HAERVRPAHR 61 DLLGPAAADS TDECVLLRAA AKVVAALPVN RPEGLDAIED LHIWTAESVR ADRLDFRPKH 121 RLAVLVVSAI PLAEPVRLAR TPEYGGCTSW VQLPVTPTLA APVHDEAALA EVAARVREAV 181 G //