LOCUS SIU01461.1 303 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 CRISPR- associated protein Csm6 protein. ACCESSION LT708304-2875 PROTEIN_ID SIU01461.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /gene="csm6" /locus_tag="BQ2027_MB2842C" /note="Mb2842c, -, len: 303 aa. Equivalent to 5' end of Rv2818c, len: 382 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 303 aa overlap). Hypothetical unknown protein, equivalent to AAK47210 from Mycobacterium tuberculosis strain CDC1551 (430 aa) but shorter 48 aa. REMARK-M.bovis-M.tuberculosis: In Mycobacterium bovis, a single base transition (c-t) introduces a premature stop codon that leads to a shorter product compared to its homolog in Mycobacterium tuberculosis strain H37Rv (303 aa versus 382 aa). Protein product from Mb2842c detected using SWATH mass spectrometry. Mb2842c found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="InterPro:IPR013489" /db_xref="UniProtKB/TrEMBL:A0A1R3Y2B3" BEGIN 1 MLFLSAEIAA FENADRRYSA AITRLAPETD VRIVTYTNPS VHRFDLFVPV FRNHLVELSA 61 EFPDRTILLN TSSGTPAMQA ALVAINVFGI PRTTAVQVST PARALSKPGD RESPDAYDLE 121 LMWDANDDNQ PGAPNRCFEA TSAALGALLE RANLKQLIVS YDYSAAVTIA ADSRLPDQVS 181 NLIRGAMHRS RLEHLVAPKF FKDTAFTYDP ANKVAEYISA LALLAKREQW AEFARSATPA 241 ITIVLRAAVA KHLPEDRYLD DMGRVDRRKL EREPEIRCAL KHPPKSPNAE WYLYTKDWLA 301 LLR //