LOCUS       SIU01461.1               303 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 CRISPR-
            associated protein Csm6 protein.
ACCESSION   LT708304-2875
PROTEIN_ID  SIU01461.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="csm6"
                     /locus_tag="BQ2027_MB2842C"
                     /note="Mb2842c, -, len: 303 aa. Equivalent to 5' end of
                     Rv2818c, len: 382 aa, from Mycobacterium tuberculosis
                     strain H37Rv, (100.0% identity in 303 aa overlap).
                     Hypothetical unknown protein, equivalent to AAK47210 from
                     Mycobacterium tuberculosis strain CDC1551 (430 aa) but
                     shorter 48 aa. REMARK-M.bovis-M.tuberculosis: In
                     Mycobacterium bovis, a single base transition (c-t)
                     introduces a premature stop codon that leads to a shorter
                     product compared to its homolog in Mycobacterium
                     tuberculosis strain H37Rv (303 aa versus 382 aa). Protein
                     product from Mb2842c detected using SWATH mass
                     spectrometry. Mb2842c found to be expressed during
                     exponential growth in Sauton's minimal media by
                     RNA-sequencing."
                     /db_xref="InterPro:IPR013489"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3Y2B3"
BEGIN
        1 MLFLSAEIAA FENADRRYSA AITRLAPETD VRIVTYTNPS VHRFDLFVPV FRNHLVELSA
       61 EFPDRTILLN TSSGTPAMQA ALVAINVFGI PRTTAVQVST PARALSKPGD RESPDAYDLE
      121 LMWDANDDNQ PGAPNRCFEA TSAALGALLE RANLKQLIVS YDYSAAVTIA ADSRLPDQVS
      181 NLIRGAMHRS RLEHLVAPKF FKDTAFTYDP ANKVAEYISA LALLAKREQW AEFARSATPA
      241 ITIVLRAAVA KHLPEDRYLD DMGRVDRRKL EREPEIRCAL KHPPKSPNAE WYLYTKDWLA
      301 LLR
//