LOCUS       SIU01456.1               270 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 Type
            II secretory pathway, component ExeA protein.
ACCESSION   LT708304-2870
PROTEIN_ID  SIU01456.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB2837"
                     /note="Mb2837, -, len: 270 aa. Equivalent to Rv2813, len:
                     270 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (99.6% identity in 270 aa overlap). Conserved hypothetical
                     protein, similar to various proteins (notably secreted
                     proteins) e.g. Q9ZFL2 HYPOTHETICAL 30.4 KDA PROTEIN from
                     Bacillus stearothermophilus (266 aa), FASTA scores: opt:
                     518, E(): 1.4e-26, (33.85% identity in 266 aa overlap);
                     P45754|GSPA_AERHY|EXEA GENERAL SECRETION PATHWAY PROTEIN
                     from Aeromonas hydrophila (547 aa), FASTA scores: opt:
                     386, E(): 1.1e-17, (32.05% identity in 265 aa overlap);
                     Q9KPC7|VC2445 GENERAL SECRETION PATHWAY PROTEIN A from
                     Vibrio cholerae (529 aa), FASTA scores: opt: 366, E():
                     2.2e-16, (31.1% identity in 270 aa overlap); Q56674|VC0403
                     MANNOSE-SENSITIVE HEMAGGLUTININ D from Vibrio cholerae
                     (281 aa), FASTA scores: opt: 317, E(): 2.1e-13, (27.85%
                     identity in 262 aa overlap); etc. Also highly similar to
                     AAK40072 Rv2813-LIKE PROTEIN from Mycobacterium celatum
                     (270 aa), FASTA scores: opt: 1628, E(): 2.8e-99, (90.75%
                     identity in 270 aa overlap). Contains PS00017
                     ATP/GTP-binding site motif A (P-loop)."
                     /db_xref="InterPro:IPR003593"
                     /db_xref="InterPro:IPR027417"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3Y331"
BEGIN
        1 MMHKLISYYG FSRMPFGRDL APGMLHRHSA HNEAVARIGW CIADRRIGVI TGEVGAGKTV
       61 AVRAALASLD RSRHTVIYLP DPTVGVQGIH HRIVASLGGQ PLTHHATLAP QAADALAAEQ
      121 AERGRTPVVV VEEAHLLGYD QLEALRLLTN HDLDSSSPFA CLLIGQPTLR RRMKLGVLAA
      181 LDQRIGLRYA MPPMTDTNTG SYLRHHLKLA GRDDALFSDD AIGLIHQTSR GYPRAVNNLA
      241 LQALVAAFAA DKAIVDESTT RTAIAEVTAD
//