LOCUS       SIU01430.1               410 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE
            ACYL-CoA DEHYDROGENASE FADE21 protein.
ACCESSION   LT708304-2844
PROTEIN_ID  SIU01430.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="fadE21"
                     /locus_tag="BQ2027_MB2812C"
                     /note="Mb2812c, fadE21, len: 410 aa. Equivalent to
                     Rv2789c, len: 410 aa, from Mycobacterium tuberculosis
                     strain H37Rv, (100.0% identity in 410 aa overlap).
                     Probable fadE21, acyl-CoA dehydrogenase (EC 1.3.99.-),
                     similar to many e.g. P45857|ACDB_BACSU|MMGC from Bacillus
                     subtilis (379 aa), FASTA scores: opt: 689, E(): 9.3e-37,
                     (35.75% identity in 400 aa overlap); Q9K6D1|ACDA|BH3798
                     from Bacillus halodurans (380 aa), FASTA scores: opt: 679,
                     E(): 4.1e-36, (37.3% identity in 405 aa overlap);
                     Q06319|ACDS_MEGEL from Megasphaera elsdenii (383 aa),
                     FASTA scores: opt: 650, E(): 3e-34, (37.7% identity in 334
                     aa overlap); etc. Contains acyl-CoA dehydrogenases
                     signature 1 (PS00072). BELONGS TO THE ACYL-COA
                     DEHYDROGENASES FAMILY. Protein product from Mb2812c
                     detected using shotgun mass spectrometry and SWATH mass
                     spectrometry. Mb2812c found to be expressed during
                     exponential growth in Sauton's minimal media by
                     RNA-sequencing."
                     /db_xref="GOA:A0A1R3Y270"
                     /db_xref="InterPro:IPR006089"
                     /db_xref="InterPro:IPR006091"
                     /db_xref="InterPro:IPR009075"
                     /db_xref="InterPro:IPR009100"
                     /db_xref="InterPro:IPR013786"
                     /db_xref="InterPro:IPR036250"
                     /db_xref="InterPro:IPR037069"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3Y270"
                     /experiment="experimental evidence, no additional details
                     recorded"
BEGIN
        1 MFEWSDTDLM VRDAVRQFID KEIRPHQDAL ETGELSPYPI ARKLFSQFGL DVLLAESVNQ
       61 MLDGERAKRE KRDSSGSFGL ADQASMVAVL VSELAGVSIG LLSTVAVSLG LGAATIMSRG
      121 TLAQQERWVP TLVTLEKIAA WAITEPDSGS DAFGGMKTHV TRDGEDYILN GHKTFITNGP
      181 YADVLVVYAK LADGEPASDW RNRPVLVFVL DAGMPGLTQG KPFKKMGMMS SPTGELFFDN
      241 VRLTPDRLLC AEGDGRDSAR ANFAVERLGV ALMSLGIINE CHRLCVDYAK TRTLWGRNIG
      301 QFQLIQLKLA KMEVARINVQ NMVFQAIERL KAGKQLTLAE ASAIKLYSSE AATDVAMEAV
      361 QLFGGNGYMA EYRVEQLARD AKSLMIYAGS NEVQVTHIAK GLLGEPASRA
//