LOCUS SIU01410.1 382 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 ppe family protein ppe44 protein. ACCESSION LT708304-2824 PROTEIN_ID SIU01410.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /gene="PPE44" /locus_tag="BQ2027_MB2792C" /note="Mb2792c, PPE44, len: 382 aa. Equivalent to Rv2770c, len: 382 aa, from Mycobacterium tuberculosis strain H37Rv, (99.7% identity in 382 aa overlap). Member of the Mycobacterium tuberculosis PPE family, highly similar to many e.g. downstream ORF O33310|Rv2768c|MTV002.33c from M. tuberculosis (394 aa), FASTA scores: opt: 1135, E(): 2.2e-53, (62.15% identity in 391 aa overlap); and P96362|Rv1039c|MTCY10G2.10 from Mycobacterium tuberculosis (391 aa), FASTA scores: opt: 1010, E(): 1e-46, (55.95% identity in 395 aa overlap). Equivalent to AAK47159 from M. tuberculosis strain CDC1551 (402 aa) but shorter 20 aa. Start changed since first submission (-20 aa). Mb2792c found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing (TPM > 20)." /db_xref="InterPro:IPR000030" /db_xref="InterPro:IPR022171" /db_xref="InterPro:IPR038332" /db_xref="UniProtKB/TrEMBL:A0A1R3Y245" /experiment="experimental evidence, no additional details recorded" BEGIN 1 MDFGALPPEV NSARMYGGAG AADLLAAAAA WNGIAVEVST AASSVGSVIT RLSTEHWMGP 61 ASLSMAAAVQ PYLVWLTCTA ESSALAAAQA MASAAAFETA FALTVPPAEV VANRALLAEL 121 TATNILGQNV SAIAATEARY GEMWAQDASA MYGYAAASAV AARLNPLTRP SHITNPAGLA 181 HQAAAVGQAG ASASARQVGL SHLISDVADA VLSFASPVMS AADTGLEAVR QFLNLDVPLF 241 VESAFHGLGG VADFATAAIG NMTLLADAMG TVGGAAPGGG AAAAVAHAVA PAGVGGTALT 301 ADLGNASVVG RLSVPASWST AAPATAAGAA LDGTGWAVPE EDGPIAVMPP APGMVVAANS 361 VGADSGPRYG VKPIVMPKHG LF //