LOCUS       SIU01410.1               382 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 ppe
            family protein ppe44 protein.
ACCESSION   LT708304-2824
PROTEIN_ID  SIU01410.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="PPE44"
                     /locus_tag="BQ2027_MB2792C"
                     /note="Mb2792c, PPE44, len: 382 aa. Equivalent to Rv2770c,
                     len: 382 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (99.7% identity in 382 aa overlap). Member of the
                     Mycobacterium tuberculosis PPE family, highly similar to
                     many e.g. downstream ORF O33310|Rv2768c|MTV002.33c from M.
                     tuberculosis (394 aa), FASTA scores: opt: 1135, E():
                     2.2e-53, (62.15% identity in 391 aa overlap); and
                     P96362|Rv1039c|MTCY10G2.10 from Mycobacterium tuberculosis
                     (391 aa), FASTA scores: opt: 1010, E(): 1e-46, (55.95%
                     identity in 395 aa overlap). Equivalent to AAK47159 from
                     M. tuberculosis strain CDC1551 (402 aa) but shorter 20 aa.
                     Start changed since first submission (-20 aa). Mb2792c
                     found to be expressed during exponential growth in
                     Sauton's minimal media by RNA-sequencing (TPM > 20)."
                     /db_xref="InterPro:IPR000030"
                     /db_xref="InterPro:IPR022171"
                     /db_xref="InterPro:IPR038332"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3Y245"
                     /experiment="experimental evidence, no additional details
                     recorded"
BEGIN
        1 MDFGALPPEV NSARMYGGAG AADLLAAAAA WNGIAVEVST AASSVGSVIT RLSTEHWMGP
       61 ASLSMAAAVQ PYLVWLTCTA ESSALAAAQA MASAAAFETA FALTVPPAEV VANRALLAEL
      121 TATNILGQNV SAIAATEARY GEMWAQDASA MYGYAAASAV AARLNPLTRP SHITNPAGLA
      181 HQAAAVGQAG ASASARQVGL SHLISDVADA VLSFASPVMS AADTGLEAVR QFLNLDVPLF
      241 VESAFHGLGG VADFATAAIG NMTLLADAMG TVGGAAPGGG AAAAVAHAVA PAGVGGTALT
      301 ADLGNASVVG RLSVPASWST AAPATAAGAA LDGTGWAVPE EDGPIAVMPP APGMVVAANS
      361 VGADSGPRYG VKPIVMPKHG LF
//