LOCUS       SIU01355.1               154 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 probable
            transcriptional regulatory protein nrdr protein.
ACCESSION   LT708304-2769
PROTEIN_ID  SIU01355.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="nrdr"
                     /locus_tag="BQ2027_MB2737C"
                     /note="Mb2737c, -, len: 154 aa. Equivalent to Rv2718c,
                     len: 154 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 154 aa overlap). Conserved
                     hypothetical protein, equivalent to
                     Q49844|ML1005|U2235A|B2235_C2_209 HYPOTHETICAL 17.3 KDA
                     PROTEIN from Mycobacterium leprae (154 aa), FASTA scores:
                     opt: 937, E(): 1.5e-52, (92.7% identity in 151 aa
                     overlap). Highly similar to O86848|NRDR_STRCL PUTATIVE
                     REGULATORY PROTEIN from Streptomyces clavuligerus (172
                     aa), FASTA scores: opt: 750, E(): 1.1e-40, (73.65%
                     identity in 148 aa overlap); O69980|SC4H2.25 HYPOTHETICAL
                     PROTEIN from Streptomyces coelicolor (182 aa), FASTA
                     scores: opt: 725, E(): 4.6e-39, (73.1% identity in 145 aa
                     overlap); Q9KPU0|VC2272 HYPOTHETICAL PROTEIN from Vibrio
                     cholerae (156 aa), FASTA scores: opt: 462, E(): 1.8e-22,
                     (47.3% identity in 148 aa overlap); etc. Protein product
                     from Mb2737c detected using shotgun mass spectrometry and
                     SWATH mass spectrometry. Mb2737c found to be expressed
                     during exponential growth in Sauton's minimal media by
                     RNA-sequencing."
                     /db_xref="GOA:P67314"
                     /db_xref="InterPro:IPR003796"
                     /db_xref="InterPro:IPR005144"
                     /db_xref="UniProtKB/Swiss-Prot:P67314"
BEGIN
        1 MHCPFCRHPD SRVIDSRETD EGQAIRRRRS CPECGRRFTT VETAVLAVVK RSGVTEPFSR
       61 EKVISGVRRA CQGRQVDDDA LNLLAQQVED SVRAAGSPEI PSHDVGLAIL GPLRELDEVA
      121 YLRFASVYRS FSSADDFARE IEALRAHRNL SAHS
//