LOCUS       SIU01324.1               237 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 antibiotic-
            transport integral membrane leucine and valine rich protein
            abc transporter protein.
ACCESSION   LT708304-2738
PROTEIN_ID  SIU01324.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB2706C"
                     /note="Mb2706c, -, len: 237 aa. Equivalent to Rv2687c,
                     len: 237 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 237 aa overlap). Probable
                     antibiotic-transport integral membrane leu-, val-rich
                     protein ABC transporter (see citation below), showing some
                     similarity with two other hypothetical proteins,
                     BAB59668|TVG0517148 from Thermoplasma volcanium (241 aa),
                     FASTA scores: opt: 136, E(): 0.32, (23.1% identity in 208
                     aa overlap); and Q97U55|SSO3168 from Sulfolobus
                     solfataricus (249 aa), FASTA scores: opt: 136, E(): 0.33,
                     (25.15% identity in 195 aa overlap). Has some hydrophobic
                     stretches and contains bacterial regulatory proteins, araC
                     family signature (PS00041). Mb2706c found to be expressed
                     during exponential growth in Sauton's minimal media by
                     RNA-sequencing."
                     /db_xref="GOA:A0A1R3Y1W6"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3Y1W6"
BEGIN
        1 MTRLVPALRL ELTLQVRQKF LHAAVFSGLI WLAVLLPMPV SLRPVAEPYV LVGDIAIIGF
       61 FFVGGTVFFE KQERTIGAIV STPLRFWEYL AAKLTVLLAI SLFVAVVVAT IVHGLGYHLL
      121 PLVAGIVLGT LLMLLVGFSS SLPFASVTDW FLAAVIPLAI MLAPPVVHYS GLWPNPVLYL
      181 IPTQGPLLLL GAAFDQVSLA PWQVGYAVVY PIVCAAGLCR AAKALFGRYV VQRSGVL
//