LOCUS SIU01278.1 413 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 conserved protein protein. ACCESSION LT708304-2692 PROTEIN_ID SIU01278.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /locus_tag="BQ2027_MB2660C" /note="Mb2660c, -, len: 413 aa. Equivalent to Rv2627c, len: 413 aa, from Mycobacterium tuberculosis strain H37Rv, (99.8% identity in 413 aa overlap). Conserved hypothetical protein. Some similarity in C-terminal part of O53697|Rv0293c|MTV035.21c HYPOTHETICAL 44.0 KDA PROTEIN from Mycobacterium tuberculosis (400 aa), FASTA scores: opt: 392, E(): 1.9e-17, (31.1% identity in 299 aa overlap). Protein product from Mb2660c detected using shotgun mass spectrometry and SWATH mass spectrometry. Mb2660c found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="InterPro:IPR029058" /db_xref="UniProtKB/TrEMBL:A0A1R3Y265" /experiment="experimental evidence, no additional details recorded" BEGIN 1 MASSASDGTH ERSAFRLSPP VLSGAMGPFM HTGLYVAQSW RDYLGQQPDK LPIARPTIAL 61 AAQAFRDEIV LLGLKARRPV SNHRVFERIS QEVAAGLEFY GNRGWLEKPS GFFAQPPPLT 121 EVAVRKVKDR RRSFYRIFFD SGFTPHPGEP GSQRWLSYTA NNREYALLLR HPEPRPWLVC 181 VHGTEMGRAP LDLAVFRAWK LHDELGLNIV MPVLPMHGPR GQGLPKGAVF PGEDVLDDVH 241 GTAQAVWDIR RLLSWIRSQE EESLIGLNGL SLGGYIASLV ASLEEGLACA ILGVPVADLI 301 ELLGRHCGLR HKDPRRHTVK MAEPIGRMIS PLSLTPLVPM PGRFIYAGIA DRLVHPREQV 361 TRLWEHWGKP EIVWYPGGHT GFFQSRPVRR FVQAALEQSG LLDAPRTQRD RSA //