LOCUS       SIU01276.1               393 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE
            CONSERVED TRANSMEMBRANE ALANINE AND LEUCINE RICH PROTEIN
            protein.
ACCESSION   LT708304-2690
PROTEIN_ID  SIU01276.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB2658C"
                     /note="Mb2658c, -, len: 393 aa. Equivalent to Rv2625c,
                     len: 393 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 393 aa overlap). Probable conserved
                     transmembrane ala-, leu-rich protein, similar to many
                     hypothetical or membrane proteins e.g.
                     Q55518|Y528_SYNY3|SLL0528 POTENTIAL INTEGRAL MEMBRANE
                     PROTEIN from Synechocystis sp. strain PCC 6803 (379 aa),
                     FASTA scores: opt: 552, E(): 5.6e-26, (30.75% identity in
                     374 aa overlap); Q9RJ56|SCI41.35c HYPOTHETICAL 39.8 KDA
                     PROTEIN from Streptomyces coelicolor (374 aa), FASTA
                     scores: opt: 419, E(): 5.7e-18, (31.6% identity in 383 aa
                     overlap); CAC49448|SMB20925 CONSERVED HYPOTHETICAL
                     MEMBRANE PROTEIN from Rhizobium meliloti (Sinorhizobium
                     meliloti) (372 aa), FASTA scores: opt: 401, E(): 6.9e-17,
                     (29.5% identity in 383 aa overlap); etc. Contains PS00142
                     Neutral zinc metallopeptidases, zinc-binding region
                     signature. Protein product from Mb2658c detected using
                     SWATH mass spectrometry. Mb2658c found to be expressed
                     during exponential growth in Sauton's minimal media by
                     RNA-sequencing."
                     /db_xref="GOA:A0A1R3Y2K2"
                     /db_xref="InterPro:IPR000644"
                     /db_xref="InterPro:IPR008915"
                     /db_xref="InterPro:IPR016483"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3Y2K2"
                     /experiment="experimental evidence, no additional details
                     recorded"
BEGIN
        1 MRDAIPLGRI AGFVVNVHWS VLVILWLFTW SLATMLPGTV GGYPAVVYWL LGAGGAVMLL
       61 ASLLAHELAH AVVARRAGVS VESVTLWLFG GVTALGGEAK TPKAAFRIAF AGPATSLALS
      121 ATFGALAITL AGVRTPAIVI SVAWWLATVN LLLGLFNLLP GAPLDGGRLV RAYLWRRHGD
      181 SVRAGIGAAR AGRVVALVLI ALGLAEFVAG GLVGGVWLAF IGWFIFAAAR EEETRISTQQ
      241 LFAGVRVADA MTAQPHTAPG WINVEDFIQR YVLGERHSAY PVADRDGSIT GLVALRQLRD
      301 VAPSRRSTTS VGDIALPLHS VPTARPQEPL TALLERMAPL GPRSRALVTE GSAVVGIVTP
      361 SDVARLIDVY RLAQPEPTFT TSPQDADRFS DAG
//