LOCUS SIU01254.1 198 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 probable glutamine amidotransferase snop protein. ACCESSION LT708304-2668 PROTEIN_ID SIU01254.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /gene="snop" /locus_tag="BQ2027_MB2636C" /note="Mb2636c, -, len: 198 aa. Equivalent to Rv2604c, len: 198 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 198 aa overlap). Conserved hypothetical protein, equivalent (but shorter 21 aa) to Q49637|HISH|B1177_C1_149 HISH PROTEIN (BELONGS TO THE YFL060C/YAAE/HI1648 FAMILY) (alias Q9CCT5|ML0474 HYPOTHETICAL PROTEIN 223 aa) from Mycobacterium leprae (219 aa), FASTA scores: opt: 1069, E(): 1.7e-60, (83.35% identity in 198 aa overlap). Also highly similar to hypothetical proteins or amidotransferases e.g. Q9L287|SCL2.12c HYPOTHETICAL 21.5 KDA PROTEIN from Streptomyces coelicolor (202 aa), FASTA scores: opt: 702, E(): 2.3e-37, (56.75% identity in 192 aa overlap); P37528|YAAE_BACSU HYPOTHETICAL 21.4 KDA PROTEIN from Bacillus subtilis (196 aa), FASTA scores: opt: 608, E(): 1.9e-31, (48.7% identity in 189 aa overlap); Q9KGN5|BH0023 AMIDOTRANSFERASE from Bacillus halodurans (196 aa), FASTA scores: opt: 583, E(): 7.4e-30, (48.7% identity in 195 aa overlap); etc. Also some similarity with several proteins from Mycobacterium tuberculosis e.g. O06589|HIS5_MYCTU|Rv1602|MT1638|MTCY336.02c AMIDOTRANSFERASE (EC 2.4.2.-) (206 aa), FASTA scores: opt: 154, E(): 0.00036, (30.6% identity in 193 aa overlap). Protein product from Mb2636c detected using SWATH mass spectrometry. Mb2636c found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="GOA:Q7TY92" /db_xref="InterPro:IPR002161" /db_xref="InterPro:IPR021196" /db_xref="InterPro:IPR029062" /db_xref="UniProtKB/Swiss-Prot:Q7TY92" BEGIN 1 MSVPRVGVLA LQGDTREHLA ALRECGAEPM TVRRRDELDA VDALVIPGGE STTMSHLLLD 61 LDLLGPLRAR LADGLPAYGS CAGMILLASE ILDAGAAGRQ ALPLRAMNMT VRRNAFGSQV 121 DSFEGDIEFA GLDDPVRAVF IRAPWVERVG DGVQVLARAA GHIVAVRQGA VLATAFHPEM 181 TGDRRIHQLF VDIVTSAA //