LOCUS       SIU01252.1               146 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 possible
            toxin vapc41. contains pin domain. protein.
ACCESSION   LT708304-2666
PROTEIN_ID  SIU01252.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="vapc41"
                     /locus_tag="BQ2027_MB2634"
                     /note="Mb2634, -, len: 146 aa. Equivalent to Rv2602, len:
                     146 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 146 aa overlap). Conserved
                     hypothetical protein, some weak similarity with proteins
                     from Mycobacterium tuberculosis (strains H37Rv and
                     CDC1551) e.g. O50457|Rv1242|MTV006.14 (143 aa), FASTA
                     scores: opt: 147, E(): 0.0021, (26.25% identity in 141 aa
                     overlap); P95023|Rv2530c|MTCY159.26 (139 aa), FASTA
                     scores: opt: 131, E(): 0.027, (33.35% identity in 135 aa
                     overlap); O53812|Rv0749|MTV041.23 (142 aa), FASTA scores:
                     opt: 125, E(): 0.072, (26.45% identity in 140 aa overlap).
                     Protein product from Mb2634 detected using SWATH mass
                     spectrometry. Mb2634 found to be expressed during
                     exponential growth in Sauton's minimal media by
                     RNA-sequencing."
                     /db_xref="GOA:A0A1R3Y1P7"
                     /db_xref="InterPro:IPR002716"
                     /db_xref="InterPro:IPR006226"
                     /db_xref="InterPro:IPR022907"
                     /db_xref="InterPro:IPR029060"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3Y1P7"
BEGIN
        1 MLLCDTNIWL ALALSGHVHH RASRAWLDTI NAPGVIHFCR ATQQSLLRLL TNRTVLGAYG
       61 SPPLTNREAW AAYAAFLDDD RIVLAGAEPD GLEAQWRAFA VRQSPAPKVW MDAYLAAFAL
      121 TGGFELVTTD TAFTQYGGIE LRLLAK
//