LOCUS       SIU01250.1               523 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 probable
            spermidine synthase spee (putrescine aminopropyltransferase)
            (aminopropyltransferase) (spdsy) protein.
ACCESSION   LT708304-2664
PROTEIN_ID  SIU01250.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="speE"
                     /locus_tag="BQ2027_MB2632"
                     /note="Mb2632, speE, len: 523 aa. Equivalent to Rv2601,
                     len: 523 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 523 aa overlap). Probable speE,
                     spermidine synthase (EC 2.5.1.16), highly similar to many
                     e.g. Q9L091|SCC24.26c from Streptomyces coelicolor (531
                     aa), FASTA scores: opt: 1493, E(): 1.3e-79, (48.45%
                     identity in 514 aa overlap); Q9X8S2|SCH10.33c from
                     Streptomyces coelicolor (554 aa), FASTA scores: opt: 1045,
                     E(): 1.7e-53, (40.55% identity in 525 aa overlap);
                     P09158|SPEE_ECOLI|B0121 from Escherichia coli strain K12
                     (287 aa), FASTA scores: opt: 368, E(): 2.9e-14, (30.5%
                     identity in 272 aa overlap); etc. Protein product from
                     Mb2632 detected using SWATH mass spectrometry."
                     /db_xref="GOA:Q7TY95"
                     /db_xref="InterPro:IPR001045"
                     /db_xref="InterPro:IPR029063"
                     /db_xref="InterPro:IPR030373"
                     /db_xref="InterPro:IPR030374"
                     /db_xref="UniProtKB/Swiss-Prot:Q7TY95"
BEGIN
        1 MTSTRQAGEA TEASVRWRAV LLAAVAACAA CGLVYELALL TLAASLNGGG IVATSLIVAG
       61 YIAALGAGAL LIKPLLAHAA IAFIAVEAVL GIIGGLSAAA LYAAFAFLDE LDGSTLVLAV
      121 GTALIGGLVG AEVPLLMTLL QRGRVAGAAD AGRTLANLNA ADYLGALVGG LAWPFLLLPQ
      181 LGMIRGAAVT GIVNLAAAGV VSIFLLRHVV SGRQLVTALC ALAAALGLIA TLLVHSHDIE
      241 TTGRQQLYAD PIIAYRHSAY QEIVVTRRGD DLRLYLDGGL QFCTRDEYRY TESLVYPAVS
      301 DGARSVLVLG GGDGLAAREL LRQPGIEQIV QVELDPAVIE LARTTLRDVN AGSLDNPRVH
      361 VVIDDAMSWL RGAAVPPAGF DAVIVDLRDP DTPVLGRLYS TEFYALAARA LAPGGLMVVQ
      421 AGSPYSTPTA FWRIISTIRS AGYAVTPYHV HVPTFGDWGF ALARLTDIAP TPAVPSTAPA
      481 LRFLDQQVLE AATVFSGDIR PRTLDPSTLD NPHIVEDMRH GWD
//