LOCUS SIU01250.1 523 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 probable spermidine synthase spee (putrescine aminopropyltransferase) (aminopropyltransferase) (spdsy) protein. ACCESSION LT708304-2664 PROTEIN_ID SIU01250.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /gene="speE" /locus_tag="BQ2027_MB2632" /note="Mb2632, speE, len: 523 aa. Equivalent to Rv2601, len: 523 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 523 aa overlap). Probable speE, spermidine synthase (EC 2.5.1.16), highly similar to many e.g. Q9L091|SCC24.26c from Streptomyces coelicolor (531 aa), FASTA scores: opt: 1493, E(): 1.3e-79, (48.45% identity in 514 aa overlap); Q9X8S2|SCH10.33c from Streptomyces coelicolor (554 aa), FASTA scores: opt: 1045, E(): 1.7e-53, (40.55% identity in 525 aa overlap); P09158|SPEE_ECOLI|B0121 from Escherichia coli strain K12 (287 aa), FASTA scores: opt: 368, E(): 2.9e-14, (30.5% identity in 272 aa overlap); etc. Protein product from Mb2632 detected using SWATH mass spectrometry." /db_xref="GOA:Q7TY95" /db_xref="InterPro:IPR001045" /db_xref="InterPro:IPR029063" /db_xref="InterPro:IPR030373" /db_xref="InterPro:IPR030374" /db_xref="UniProtKB/Swiss-Prot:Q7TY95" BEGIN 1 MTSTRQAGEA TEASVRWRAV LLAAVAACAA CGLVYELALL TLAASLNGGG IVATSLIVAG 61 YIAALGAGAL LIKPLLAHAA IAFIAVEAVL GIIGGLSAAA LYAAFAFLDE LDGSTLVLAV 121 GTALIGGLVG AEVPLLMTLL QRGRVAGAAD AGRTLANLNA ADYLGALVGG LAWPFLLLPQ 181 LGMIRGAAVT GIVNLAAAGV VSIFLLRHVV SGRQLVTALC ALAAALGLIA TLLVHSHDIE 241 TTGRQQLYAD PIIAYRHSAY QEIVVTRRGD DLRLYLDGGL QFCTRDEYRY TESLVYPAVS 301 DGARSVLVLG GGDGLAAREL LRQPGIEQIV QVELDPAVIE LARTTLRDVN AGSLDNPRVH 361 VVIDDAMSWL RGAAVPPAGF DAVIVDLRDP DTPVLGRLYS TEFYALAARA LAPGGLMVVQ 421 AGSPYSTPTA FWRIISTIRS AGYAVTPYHV HVPTFGDWGF ALARLTDIAP TPAVPSTAPA 481 LRFLDQQVLE AATVFSGDIR PRTLDPSTLD NPHIVEDMRH GWD //