LOCUS       SIU01227.1               340 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 Radical
            SAM domain protein protein.
ACCESSION   LT708304-2641
PROTEIN_ID  SIU01227.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB2609C"
                     /note="Mb2609c, -, len: 340 aa. Equivalent to Rv2578c,
                     len: 340 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 340 aa overlap). Conserved
                     hypothetical protein, highly similar to hypothetical
                     proteins (conserved or not) e.g. Q9ZBJ3|SC9C7.17c from
                     Streptomyces coelicolor (348 aa), FASTA scores: opt: 998,
                     E(): 1.6e-55, (47.6% identity in 355 aa overlap);
                     Q9I763|PA0069 from Pseudomonas aeruginosa (352 aa), FASTA
                     scores: opt: 560, E(): 6e-28, (36.6% identity in 284 aa
                     overlap); Q986C9|MLL7417 from Rhizobium loti
                     (Mesorhizobium loti) (356 aa), FASTA scores: opt: 550,
                     E(): 2.6e-27, (39.15% identity in 240 aa overlap); etc.
                     Mb2609c found to be expressed during exponential growth in
                     Sauton's minimal media by RNA-sequencing (TPM > 20)."
                     /db_xref="GOA:P65024"
                     /db_xref="InterPro:IPR006638"
                     /db_xref="InterPro:IPR007197"
                     /db_xref="InterPro:IPR013785"
                     /db_xref="InterPro:IPR040086"
                     /db_xref="UniProtKB/Swiss-Prot:P65024"
BEGIN
        1 MRWARQAVAV NGMPVDDGAL PGLQRIGLVR SVRAPQFDGI TFHEVLCKSA LNKVPNAAAL
       61 PFRYTVNGYR GCSHACRYCF ARPTHEYLDF NPGTDFDTQV VVKTNVAAVL RHELRRPSWR
      121 RETVALGTNT DPYQRAEGRY ALMPGIIGAL AASGTPLSIL TKGTLLRRDL PLIAEAAQQV
      181 PVSVAVSLAV GDPELHRDVE SGTPTPQARL ALITAIRAAG LDCHVMVAPV LPQLTDSGEH
      241 LDQLLGQIAA AGATGVTVFG LHLRGSTRGW FMCWLARAHP ELVSRYRELY RRGPYLPPSY
      301 REMLRERVAP LIAKYRLAGD HRPAPPETEA ALVPVQATLF
//