LOCUS SIU01227.1 340 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 Radical SAM domain protein protein. ACCESSION LT708304-2641 PROTEIN_ID SIU01227.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /locus_tag="BQ2027_MB2609C" /note="Mb2609c, -, len: 340 aa. Equivalent to Rv2578c, len: 340 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 340 aa overlap). Conserved hypothetical protein, highly similar to hypothetical proteins (conserved or not) e.g. Q9ZBJ3|SC9C7.17c from Streptomyces coelicolor (348 aa), FASTA scores: opt: 998, E(): 1.6e-55, (47.6% identity in 355 aa overlap); Q9I763|PA0069 from Pseudomonas aeruginosa (352 aa), FASTA scores: opt: 560, E(): 6e-28, (36.6% identity in 284 aa overlap); Q986C9|MLL7417 from Rhizobium loti (Mesorhizobium loti) (356 aa), FASTA scores: opt: 550, E(): 2.6e-27, (39.15% identity in 240 aa overlap); etc. Mb2609c found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing (TPM > 20)." /db_xref="GOA:P65024" /db_xref="InterPro:IPR006638" /db_xref="InterPro:IPR007197" /db_xref="InterPro:IPR013785" /db_xref="InterPro:IPR040086" /db_xref="UniProtKB/Swiss-Prot:P65024" BEGIN 1 MRWARQAVAV NGMPVDDGAL PGLQRIGLVR SVRAPQFDGI TFHEVLCKSA LNKVPNAAAL 61 PFRYTVNGYR GCSHACRYCF ARPTHEYLDF NPGTDFDTQV VVKTNVAAVL RHELRRPSWR 121 RETVALGTNT DPYQRAEGRY ALMPGIIGAL AASGTPLSIL TKGTLLRRDL PLIAEAAQQV 181 PVSVAVSLAV GDPELHRDVE SGTPTPQARL ALITAIRAAG LDCHVMVAPV LPQLTDSGEH 241 LDQLLGQIAA AGATGVTVFG LHLRGSTRGW FMCWLARAHP ELVSRYRELY RRGPYLPPSY 301 REMLRERVAP LIAKYRLAGD HRPAPPETEA ALVPVQATLF //