LOCUS SIU01223.1 293 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 POSSIBLE CONSERVED MEMBRANE GLYCINE RICH PROTEIN protein. ACCESSION LT708304-2637 PROTEIN_ID SIU01223.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /locus_tag="BQ2027_MB2605" /note="Mb2605, -, len: 293 aa. Equivalent to Rv2575, len: 293 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 293 aa overlap). Possible conserved membrane gly-rich protein, highly similar to hypothetical proteins e.g. Q9RR98|DR2596 CONSERVED HYPOTHETICAL PROTEIN from Deinococcus radiodurans (313 aa), FASTA scores: opt: 734, E(): 2.8e-38, (42.95% identity in 291 aa overlap); Q9HV81|PA4717 from Pseudomonas aeruginosa (297 aa), FASTA scores: opt: 641, E(): 1.5e-32, (43.35% identity in 300 aa overlap); Q98IA4|MLL2493 from Rhizobium loti (Mesorhizobium loti) (306 aa), FASTA scores: opt: 628, E(): 1e-31, (38.45% identity in 307 aa overlap); etc. Contains PS00142 Neutral zinc metallopeptidases, zinc-binding region signature. Protein product from Mb2605 detected using shotgun mass spectrometry and SWATH mass spectrometry. Mb2605 found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="GOA:P65020" /db_xref="InterPro:IPR007343" /db_xref="UniProtKB/Swiss-Prot:P65020" BEGIN 1 MTFNEGVQID TSTTSTSGSG GGRRLAIGGG LGGLLVVVVA MLLGVDPGGV LSQQPLDTRD 61 HVAPGFDLSQ CRTGADANRF VQCRVVATGN SVDAVWKPLL PGYTRPHMRL FSGQVGTGCG 121 PASSEVGPFY CPVDKTAYFD TDFFQVLVTQ FGSSGGPFAE EYVVAHEYGH HVQNLLGVLG 181 RAQQGAQGAA GSGVRTELQA DCYAGVWAYY ASTVKQESTG VPYLEPLSDK DIQDALAAAA 241 AVGDDRIQQQ TTGRTNPETW THGSAAQRQK WFTVGYQTGD PNICDTFSAA DLG //