LOCUS       SIU01223.1               293 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 POSSIBLE
            CONSERVED MEMBRANE GLYCINE RICH PROTEIN protein.
ACCESSION   LT708304-2637
PROTEIN_ID  SIU01223.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB2605"
                     /note="Mb2605, -, len: 293 aa. Equivalent to Rv2575, len:
                     293 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 293 aa overlap). Possible conserved
                     membrane gly-rich protein, highly similar to hypothetical
                     proteins e.g. Q9RR98|DR2596 CONSERVED HYPOTHETICAL PROTEIN
                     from Deinococcus radiodurans (313 aa), FASTA scores: opt:
                     734, E(): 2.8e-38, (42.95% identity in 291 aa overlap);
                     Q9HV81|PA4717 from Pseudomonas aeruginosa (297 aa), FASTA
                     scores: opt: 641, E(): 1.5e-32, (43.35% identity in 300 aa
                     overlap); Q98IA4|MLL2493 from Rhizobium loti
                     (Mesorhizobium loti) (306 aa), FASTA scores: opt: 628,
                     E(): 1e-31, (38.45% identity in 307 aa overlap); etc.
                     Contains PS00142 Neutral zinc metallopeptidases,
                     zinc-binding region signature. Protein product from Mb2605
                     detected using shotgun mass spectrometry and SWATH mass
                     spectrometry. Mb2605 found to be expressed during
                     exponential growth in Sauton's minimal media by
                     RNA-sequencing."
                     /db_xref="GOA:P65020"
                     /db_xref="InterPro:IPR007343"
                     /db_xref="UniProtKB/Swiss-Prot:P65020"
BEGIN
        1 MTFNEGVQID TSTTSTSGSG GGRRLAIGGG LGGLLVVVVA MLLGVDPGGV LSQQPLDTRD
       61 HVAPGFDLSQ CRTGADANRF VQCRVVATGN SVDAVWKPLL PGYTRPHMRL FSGQVGTGCG
      121 PASSEVGPFY CPVDKTAYFD TDFFQVLVTQ FGSSGGPFAE EYVVAHEYGH HVQNLLGVLG
      181 RAQQGAQGAA GSGVRTELQA DCYAGVWAYY ASTVKQESTG VPYLEPLSDK DIQDALAAAA
      241 AVGDDRIQQQ TTGRTNPETW THGSAAQRQK WFTVGYQTGD PNICDTFSAA DLG
//