LOCUS       SIU01210.1               349 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE
            GLUTAMINE-TRANSPORT TRANSMEMBRANE PROTEIN ABC TRANSPORTER
            protein.
ACCESSION   LT708304-2624
PROTEIN_ID  SIU01210.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB2592"
                     /note="Mb2592, -, len: 349 aa. Equivalent to Rv2563, len:
                     349 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 349 aa overlap). Probable
                     glutamine-transport transmembrane protein ABC transporter
                     (see citation below), highly similar to
                     O53617|Rv0072|MTV030.16 PUTATIVE ABC-TRANSPORTER
                     TRANSMEMBRANE SUBUNIT from Mycobacterium tuberculosis (349
                     aa), FASTA scores: opt: 1772, E(): 1.1e-89, (76.2%
                     identity in 349 aa overlap). Also some similarity with
                     various hypothetical proteins e.g. Q9RYN1|DRA0279
                     HYPOTHETICAL 37.1 KDA PROTEIN from Deinococcus radiodurans
                     (353 aa), FASTA scores: opt: 347, E(): 6.6e-12, (24.35%
                     identity in 357 aa overlap); BAB58522|SAV2360 CONSERVED
                     HYPOTHETICAL PROTEIN from Staphylococcus aureus subsp.
                     aureus Mu50 (351 aa), FASTA scores: opt: 262, E():
                     2.9e-07, (19.4% identity in 356 aa overlap);
                     Q9AK94|SC10A9.10c PUTATIVE ABC TRANSPORT SYSTEM
                     TRANSMEMBRANE PROTEIN from Streptomyces coelicolor (379
                     aa), FASTA scores: opt: 172, E(): 0.025, (26.85% identity
                     in 387 aa overlap); etc. Protein product from Mb2592
                     detected using shotgun mass spectrometry and SWATH mass
                     spectrometry. Mb2592 found to be expressed during
                     exponential growth in Sauton's minimal media by
                     RNA-sequencing."
                     /db_xref="GOA:P65008"
                     /db_xref="UniProtKB/Swiss-Prot:P65008"
BEGIN
        1 MLFAALRDVQ WRKRRLVIAI VSTGLVFAMT LVLTGLVNGF RVEAERTVDS MGVDAFVVKA
       61 GAAGPFLGST PFAQIDLPQV ARAPGVLAAA PLATAPSTIR QGTSARNVTA FGAPEHGPGM
      121 PRVSDGRAPS TPDEVAVSST LGRNLGDDLQ VGARTLRIVG IVPESTALAK IPNIFLTTEG
      181 LQQLAYNGQP TISSIGIDGM PRQLPDGYQT VNRADAVSDL MRPLKVAVDA ITVVAVLLWI
      241 VAALIVGSVV YLSALERLRD FAVFKAIGVP TRSILAGLAL QAVVVALLAA VVGGILSLLL
      301 APLFPMTVVV PLSAFVALPA IATVIGLLAS VAGLRRVVAI DPALAFGGP
//