LOCUS       SIU01197.1               131 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 possible
            toxin vapc20 protein.
ACCESSION   LT708304-2611
PROTEIN_ID  SIU01197.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="vapc20"
                     /locus_tag="BQ2027_MB2579C"
                     /note="Mb2579c, -, len:131 aa. Equivalent to Rv2549c, len:
                     131 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 131 aa overlap). Conserved
                     hypothetical protein, showing some similarity to
                     P73415|SLL1715 from Synechocystis sp. strain PCC 6803 (157
                     aa), FASTA scores: opt: 167, E(): 4.2e-05, (29.45%
                     identity in 129 aa overlap); Q9HHY6|VNG6166H from
                     Halobacterium sp. plasmid pNRC200 strain NRC-1 (144 aa),
                     FASTA scores: opt: 133, E(): 0.011, (29.6% identity in 125
                     aa overlap); and Q9HSU3|VNG0072H from Halobacterium sp.
                     strain NRC-1 (144 aa), FASTA scores: opt: 113, E(): 0.29,
                     (25.75% identity in 136 aa overlap). Mb2579c found to be
                     expressed during exponential growth in Sauton's minimal
                     media by RNA-sequencing."
                     /db_xref="GOA:A0A1R3Y1S7"
                     /db_xref="InterPro:IPR002716"
                     /db_xref="InterPro:IPR022907"
                     /db_xref="InterPro:IPR029060"
                     /db_xref="InterPro:IPR039018"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3Y1S7"
BEGIN
        1 MIFVDTSFWA ALGNAGDARH GTAKRLWASK PPVVMTSNHV LGETWTLLNR RCGHRAAVAA
       61 AAIRLSTVVR VEHVTADLEE QAWEWLVRHD EREYSFVDAT SFAVMRKKGI QNAYAFDGDF
      121 SAAGFVEVRP E
//