LOCUS       SIU01180.1               187 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE
            ELONGATION FACTOR P EFP protein.
ACCESSION   LT708304-2594
PROTEIN_ID  SIU01180.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="efp"
                     /locus_tag="BQ2027_MB2563C"
                     /note="Mb2563c, efp, len: 187 aa. Equivalent to Rv2534c,
                     len: 187 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 187 aa overlap). Probable efp,
                     elongation factor P, equivalent to Q9CCS0|EFP|ML0522
                     ELONGATION FACTOR P from Mycobacterium leprae (187 aa),
                     FASTA scores: opt: 1158, E(): 2.1e-67, (94.1% identity in
                     186 aa overlap). Also highly similar to many e.g.
                     Q45288|EFP_CORGL from Corynebacterium glutamicum
                     (Brevibacterium flavum) (187 aa), FASTA scores: opt: 843,
                     E(): 3.4e-47, (69.5% identity in 187 aa overlap);
                     Q9KXQ9|EFP from Streptomyces coelicolor (188 aa), FASTA
                     scores: opt: 833, E(): 1.5e-46, (67.0% identity in 188 aa
                     overlap); P49778|EFP_BACSU from Bacillus subtilis (185
                     aa), FASTA scores: opt: 607, E(): 4.6e-32, (47.8% identity
                     in 182 aa overlap); P33398|EFP_ECOLI|B4147 from
                     Escherichia coli strain K12 (187 aa), FASTA scores: opt:
                     503, E(): 1.8e-27, (42.3% identity in 182 aa overlap);
                     etc. BELONGS TO THE ELONGATION FACTOR P FAMILY. Protein
                     product from Mb2563c detected using shotgun mass
                     spectrometry and SWATH mass spectrometry. Mb2563c found to
                     be expressed during exponential growth in Sauton's minimal
                     media by RNA-sequencing (TPM > 20)."
                     /db_xref="GOA:P64035"
                     /db_xref="InterPro:IPR001059"
                     /db_xref="InterPro:IPR008991"
                     /db_xref="InterPro:IPR011768"
                     /db_xref="InterPro:IPR012340"
                     /db_xref="InterPro:IPR013185"
                     /db_xref="InterPro:IPR013852"
                     /db_xref="InterPro:IPR014722"
                     /db_xref="InterPro:IPR015365"
                     /db_xref="InterPro:IPR020599"
                     /db_xref="UniProtKB/Swiss-Prot:P64035"
                     /experiment="experimental evidence, no additional details
                     recorded"
BEGIN
        1 MATTADFKNG LVLVIDGQLW TITEFQHVKP GKGPAFVRTK LKNVLSGKVV DKTFNAGVKV
       61 DTATVDRRDT TYLYRDGSDF VFMDSQDYEQ HPLPEALVGD AARFLLEGMP VQVAFHNGVP
      121 LYIELPVTVE LEVTHTEPGL QGDRSSAGTK PATLQTGAQI NVPLFINTGD KLKVDSRDGS
      181 YLGRVNA
//