LOCUS       SIU01172.1               133 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 possible
            toxin vapc17 protein.
ACCESSION   LT708304-2586
PROTEIN_ID  SIU01172.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="vapc17"
                     /locus_tag="BQ2027_MB2556"
                     /note="Mb2556, -, len: 133 aa. Equivalent to Rv2527, len:
                     133 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 133 aa overlap). Hypothetical protein,
                     showing some similarity to hypothetical proteins from
                     Mycobacterium tuberculosis e.g. P95007|MTCY159.10c|Rv2546
                     (137 aa), FASTA scores: opt: 206, E(): 1.4e-07, (38.0%
                     identity in 100 aa overlap); O33299|MTV002.22c|Rv2757c
                     (138 aa), FASTA scores: opt: 201, E(): 3.1e-07, (35.7%
                     identity in 126 aa overlap); and
                     P96411|MTCY08D5.24c|Rv0229c (226 aa), FASTA scores: opt:
                     153, E(): 0.0011, (32.8% identity in 128 aa overlap).
                     Protein product from Mb2556 detected using SWATH mass
                     spectrometry. Mb2556 found to be expressed during
                     exponential growth in Sauton's minimal media by
                     RNA-sequencing."
                     /db_xref="GOA:A0A1R3Y1G9"
                     /db_xref="InterPro:IPR002716"
                     /db_xref="InterPro:IPR022907"
                     /db_xref="InterPro:IPR029060"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3Y1G9"
BEGIN
        1 MTTWILDKSA HVRLVAGATP PAGIDLTDLA ICDIGELEWL YSARSATDYD SQQTSLRAYQ
       61 ILRAPSDIFD RVRHLQRDLA HHRGMWHRTP LPDLFIAETA LHHRAGVLHH DRDYKRIAVV
      121 RPGFQACELS RGR
//