LOCUS SIU01172.1 133 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 possible toxin vapc17 protein. ACCESSION LT708304-2586 PROTEIN_ID SIU01172.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /gene="vapc17" /locus_tag="BQ2027_MB2556" /note="Mb2556, -, len: 133 aa. Equivalent to Rv2527, len: 133 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 133 aa overlap). Hypothetical protein, showing some similarity to hypothetical proteins from Mycobacterium tuberculosis e.g. P95007|MTCY159.10c|Rv2546 (137 aa), FASTA scores: opt: 206, E(): 1.4e-07, (38.0% identity in 100 aa overlap); O33299|MTV002.22c|Rv2757c (138 aa), FASTA scores: opt: 201, E(): 3.1e-07, (35.7% identity in 126 aa overlap); and P96411|MTCY08D5.24c|Rv0229c (226 aa), FASTA scores: opt: 153, E(): 0.0011, (32.8% identity in 128 aa overlap). Protein product from Mb2556 detected using SWATH mass spectrometry. Mb2556 found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="GOA:A0A1R3Y1G9" /db_xref="InterPro:IPR002716" /db_xref="InterPro:IPR022907" /db_xref="InterPro:IPR029060" /db_xref="UniProtKB/TrEMBL:A0A1R3Y1G9" BEGIN 1 MTTWILDKSA HVRLVAGATP PAGIDLTDLA ICDIGELEWL YSARSATDYD SQQTSLRAYQ 61 ILRAPSDIFD RVRHLQRDLA HHRGMWHRTP LPDLFIAETA LHHRAGVLHH DRDYKRIAVV 121 RPGFQACELS RGR //