LOCUS       SIU01155.1               215 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 oligoribonuclease
            orn protein.
ACCESSION   LT708304-2569
PROTEIN_ID  SIU01155.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="orn"
                     /locus_tag="BQ2027_MB2539"
                     /note="Mb2539, orn, len: 215 aa. Equivalent to Rv2511,
                     len: 215 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 215 aa overlap). Probable orn,
                     oligoribonuclease (EC 3.1.-.-), equivalent to
                     O07708|ORN_MYCLE|ORN|ML0427|MLCL383.34c OLIGORIBONUCLEASE
                     from Mycobacterium leprae (215 aa), FASTA scores: opt:
                     1170, E(): 3.5e-65, (84.5% identity in 213 aa overlap).
                     Also highly similar to many e.g. P57667|ORN_STRGR|ORNA
                     from Streptomyces griseus (201 aa), FASTA scores: opt:
                     807, E(): 7.7e-43, (59.0% identity in 200 aa overlap);
                     ORN_STRCO|ORNA|2SC13.01 from Streptomyces coelicolor (200
                     aa), FASTA scores: opt: 799, E(): 2.4e-42, (59.7% identity
                     in 201 aa overlap); P39287|ORN_ECOLI|B4162 from
                     Escherichia coli strain K12 (180 aa), FASTA scores: opt:
                     519, E(): 3.9e-25, (47.4% identity in 173 aa overlap);
                     etc. BELONGS TO THE OLIGORIBONUCLEASE FAMILY. Protein
                     product from Mb2539 detected using shotgun mass
                     spectrometry and SWATH mass spectrometry. Mb2539 found to
                     be expressed during exponential growth in Sauton's minimal
                     media by RNA-sequencing."
                     /db_xref="GOA:P65598"
                     /db_xref="InterPro:IPR012337"
                     /db_xref="InterPro:IPR013520"
                     /db_xref="InterPro:IPR022894"
                     /db_xref="InterPro:IPR036397"
                     /db_xref="UniProtKB/Swiss-Prot:P65598"
                     /experiment="experimental evidence, no additional details
                     recorded"
BEGIN
        1 MQDELVWIDC EMTGLDLGSD KLIEIAALVT DADLNILGDG VDVVMHADDA ALSGMIDVVA
       61 EMHSRSGLID EVKASTVDLA TAEAMVLDYI NEHVKQPKTA PLAGNSIATD RAFIARDMPT
      121 LDSFLHYRMI DVSSIKELCR RWYPRIYFGQ PPKGLTHRAL ADIHESIREL RFYRRTAFVP
      181 QPGPSTSEIA AVVAELSDGA GAQEETDSAE APQSG
//