LOCUS       SIU01143.1               185 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 POSSIBLE
            OXIDASE REGULATORY-RELATED PROTEIN protein.
ACCESSION   LT708304-2557
PROTEIN_ID  SIU01143.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB2527C"
                     /note="Mb2527c, -, len: 185 aa. Equivalent to Rv2499c,
                     len: 185 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 185 aa overlap). Possible oxidase
                     regulatory-related protein, similar to many maoC MONOAMINE
                     OXIDASE REGULATORY PROTEIN e.g. Q9RUZ1|DR1239 MAOC-RELATED
                     PROTEIN from Deinococcus radiodurans (160 aa), FASTA
                     scores: opt: 519, E(): 7.6e-28, (58.1% identity in 148 aa
                     overlap); BAB48392|MLR0905 Probable monoamine oxidase
                     regulatory protein from Rhizobium loti (Mesorhizobium
                     loti) (150 aa), FASTA scores: opt: 480, E(): 2.9e-25,
                     (49.0% identity in 149 aa overlap); Q9HN18|MAOC1|VNG2290G
                     MONOAMINE OXIDASE REGULATORY-LIKE from Halobacterium sp.
                     strain NRC-1 (208 aa), FASTA scores: opt: 419, E():
                     4.6e-21, (45.6% identity in 158 aa overlap);
                     P77455|MAOC_ECOLI|PAAZ|B1387 MaoC protein (Phenylacetic
                     acid degradation protein paaZ) from Escherichia coli
                     strain K12 (681 aa), FASTA scores: opt: 252, E(): 1.9e-09,
                     (36.0% identity in 172 aa overlap); etc. But also similar
                     to other proteins with different putative functions e.g.
                     Q9HRM9|MAOC2|VNG0626G MOLYBDENUM COFACTOR BIOSYNTHESIS
                     PROTEIN from Halobacterium sp strain NRC-1 (157 aa), FASTA
                     scores: opt: 380, E(): 1.5e-18, (45.75% identity in 153 aa
                     overlap); Q9KIF1 FKBR2 from Streptomyces hygroscopicus
                     var. ascomyceticus (175 aa), FASTA scores: opt: 355, E():
                     7.6e-17, (42.0% identity in 150 aa overlap);
                     CAC36828|Q99Q03|SAPE Spore associated protein from
                     Streptomyces coelicolor (174 aa), FASTA scores: opt: 318,
                     E(): 2.2e-14, (41.45% identity in 152 aa overlap); etc.
                     Protein product from Mb2527c detected using shotgun mass
                     spectrometry and SWATH mass spectrometry. Mb2527c found to
                     be expressed during exponential growth in Sauton's minimal
                     media by RNA-sequencing (TPM > 20)."
                     /db_xref="InterPro:IPR002539"
                     /db_xref="InterPro:IPR029069"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3Y1E5"
BEGIN
        1 MTKHAGDRES DDAVSACRVA GSTVGRRILQ RGLWFEEFQI GTTYLHRPGR TVTEADNVLF
       61 TTLTMNTQSL HLDAAWAGQQ PGFRGERLVN SMFTLSTMVG LSVAQLTLGT IVANLGFSEV
      121 SFPKPVFHGD TLYAETVCTG KRESKSRPGE GIVTLEHIAR NQHGEVVARA VRTTLVQKQS
      181 IKEAQ
//