LOCUS SIU01133.1 1150 aa PRT BCT 25-MAY-2020
DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 PE-
PGRS FAMILY PROTEIN [SECOND PART] protein.
ACCESSION LT708304-2547
PROTEIN_ID SIU01133.1
SOURCE Mycobacterium tuberculosis variant bovis AF2122/97
ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97
Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE 1
AUTHORS Malone K.M.
JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary
Medicine, Tuberculosis Molecular Microbiology Research Group,
University College Dublin, Tuberculosis Molecular Microbiology
Research Group, School of Veterinary Medicine, University College
Dublin, D4, Ireland
REFERENCE 2
AUTHORS Malone M K., Farrell D., Malone K.
JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary
Medicine, Tuberculosis Molecular Microbiology Research Group,
University College Dublin, Tuberculosis Molecular Microbiology
Research Group, School of Veterinary Medicine,, University College
Dublin, D4, Ireland
FEATURES Qualifiers
source /organism="Mycobacterium tuberculosis variant bovis
AF2122/97"
/chromosome="Mycobacterium_bovis_AF212297"
/isolate="AF2122/97"
/mol_type="genomic DNA"
/isolation_source="Mycobacterium bovis subsp. bovis strain
AF2122/97. This strain is a fully virulent strain that was
isolated in 1997 in the UK from a cow suffering necrotic
lesions in lung and bronchomediastinal lymph nodes. The
strain was also reported to infect and persist in badgers
that are considered to be a significant source of bovine
infection."
/db_xref="taxon:233413"
protein /transl_table=11
/gene="PE_PGRS43b"
/locus_tag="BQ2027_MB2517C"
/note="Mb2517c, PE_PGRS43b, len: 1150 aa. Similar to 3'
end of Rv2490c, len: 1660 aa, from Mycobacterium
tuberculosis strain H37Rv, (98.0% identity in 1150 aa
overlap). Member of the Mycobacterium tuberculosis PE
family, PGRS-subfamily of Gly-rich proteins, similar to
many e.g. AAK47971|MT3612.1 PE_PGRS family protein from
Mycobacterium tuberculosis strain CDC1551 (1715 aa), FASTA
scores: opt: 5161, E(): 1.5e-187, (51.7% identity in 1752
aa overlap); etc. REMARK-M.bovis-M.tuberculosis: In
Mycobacterium tuberculosis strain H37Rv, PE_PGRS43 exists
as a single gene. In Mycobacterium bovis, a frameshift due
to a 8 bp insertion (*-gggggggg) splits PE_PGRS43 into 2
parts, PE_PGRS43a and PE_PGRS43b."
/db_xref="UniProtKB/TrEMBL:A0A1R3Y1D6"
BEGIN
1 MTAIFLGSSG TPGEDGGNGG AGGAGGAGGA HAGDGGAGGA GGNGGAGGAG GNGAHGFNAV
61 LVSDGGNGGD GGAGGRGGDG GAGGAGGDAP AGRAGSQGVG GDGGAGGAGG APGNGGSGGR
121 GDMAFKDGDG GAGGDGGDPG AGGKGGAGGA GATEGVTGAT GATVHSGGNG GKGGNGADAT
181 VAGANGGKGG AGGNGGLVGD GGAGGDGGSG AAGANGANVG EDGADGTLSG QPGEGSEANG
241 GQGGVGGGGA GGAGGDGGAG SSALGSGGNG GRGDAGQAGG AGGAGGAGGA GGSVSGDGGP
301 GGKGGAGGAG GAGASGGGGG KGASGADSAE AVGGAGGKGG DGGVGGVGGD GGPGGDGGAG
361 GAAPAGQVGS HGVGGVGGDG GLGGAGGNGG DGGHGSDGGD GGDGGDPGAG GLGGLGGDSG
421 NGTRAASGVD ASDHGPGSGG NGGNGGNGAQ ASVAGGAGGN GGDGGNAGRV GDGGAGGNGG
481 DGAAGANGAN SGAPGSDALA LGQPGGNGGQ GDAGQAGGAG GAGGAGGSVS GDGGAGGNGG
541 AGGNGGVGAS GGAGARGANG IDSIGGTGGA GGGGGDGGAG GVGGHGGDGG VGGAAPSGTV
601 GSHGTGGVGG DGGLGGAGGV GGAGGNGGIG ITVGGAGGAG GNGGDPGAGG RGGLGGDSGN
661 GTSAANGVDA SKHGPLTGGD GGVGGNGAKA AAAGGDGGQG GDGGNAGLFG DGGAGGDGAD
721 GTAAEALGGD GGAGGAGGKG GDAGDIGDGG DGGKGGDGAH GALGGLTVAG GNGGAGGAGG
781 AGGAGGAFLG DGGNGGAGGQ GGAGRGGSPG GGGGVGGHGG AGGDAGMNGG GGTGGQGGNG
841 AAGGAGWSPD SDLKGFDGFD GGSGGAGGDG GAGGAGGTQT GDGGDGGAGG LGGAGGVGGN
901 GVDGFDINET TGRDGDGGDG GYGGWGGAGG NGGAGGSAPA GEVGNRGVGG DGGDGGSGGD
961 AGNGGLGGDG FTYLADFDGE PGGDGGDGGD GGWGRPGGQG GFGSTSGAHG KAGFGAPGGD
1021 GGDGGNGGHG GDGNGSFADA GDGGPGGNGG NGGLGGAGRD GGAPGGDGGD GGTGGSGGFG
1081 APPPRSIGGG DGGDGGRGGD GGRGAGGLTS GGVGSSGESG GSGNGRGDPG SGGSGGEGGE
1141 GGPSISVNVT
//