LOCUS SIU01121.1 161 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 Single- stranded DNA-binding protein protein. ACCESSION LT708304-2535 PROTEIN_ID SIU01121.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /locus_tag="BQ2027_MB2505C" /note="Mb2505c, -, len: 161 aa. Equivalent to Rv2478c, len: 161 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 161 aa overlap). Conserved hypothetical protein, with weak similarity with many single-strand binding proteins e.g. Q9X8U3|SCH24.29 PUTATIVE SINGLE-STRAND BINDING PROTEIN from Streptomyces coelicolor (199 aa), FASTA scores: opt: 246, E(): 4.5e-08, (31.5% identity in 162 aa overlap); P46390|SSB_MYCLE|ML2684|MLCB1913.20c SINGLE-STRAND BINDING PROTEIN (SSB) (HELIX-DESTABILIZING PROTEIN) from Mycobacterium leprae (168 aa), FASTA scores: opt: 239, E(): 1e-07, (30.8% identity in 146 aa overlap); P18310|SSBF_ECOLI SINGLE-STRAND BINDING PROTEIN from Escherichia coli (178 aa), FASTA scores: opt: 116, E(): 2.9, (25.7% identity in 140 aa overlap); etc. Also similarity with Rv0054|P71711|MTCY21D4.17|SSB_MYCTU PROBABLE SINGLE-STRAND BINDING PROTEIN from M. tuberculosis (164 aa), FASTA scores: opt: 234, E(): 2e-07, (31.75% identity in 148 aa overlap). N-terminus shorter 8 aa from AAK46855|MT2553 SINGLE-STRAND DNA BINDING PROTEIN from Mycobacterium tuberculosis strain CDC1551." /db_xref="GOA:A0A1R3Y1C2" /db_xref="InterPro:IPR000424" /db_xref="InterPro:IPR011344" /db_xref="InterPro:IPR012340" /db_xref="UniProtKB/TrEMBL:A0A1R3Y1C2" BEGIN 1 MVGHIVNDLQ RRKVGDQEVV KFRVASNSRR RTSDGGWEPG NSLFITVNCW GRLVTGVGAA 61 LGKGAPVIVV GHVYTSEYED RDGIRRSSLE MRATSVGPDL SRVIVRIEKP AYTGPSAGDL 121 PAATGTGAAG AADAPASAAD SVSDVVVDDA ITGHNPLPIS A //