LOCUS SIU01113.1 128 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 globin (oxygen-binding protein) glbo protein. ACCESSION LT708304-2527 PROTEIN_ID SIU01113.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /gene="glbO" /locus_tag="BQ2027_MB2497" /note="Mb2497, glbO, len: 128 aa. Equivalent to Rv2470, len: 128 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 128 aa overlap). Possible glbO, globin-like protein, highly similar to Q9CC59|GLBO|ML1253 HEMOGLOBIN-LIKE (OXYGEN CARRIER) from Mycobacterium leprae (128 aa), FASTA scores: opt: 767, E(): 4e-47, (88.1% identity in 126 aa overlap); Q9X7B3|MLCB1610.14c PUTATIVE GLOBIN from Mycobacterium leprae (131 aa); Q9L250|SC6D10.14 PUTATIVE GLOBIN from Streptomyces coelicolor (137 aa), FASTA scores: opt: 466, E(): 5.7e-26, (53.6% identity in 125 aa overlap). Also similar to O31607 YJBI PROTEIN from Bacillus subtilis (132 aa), FASTA scores: opt: 294, E(): 6.6e-14; (39.85% identity in 128 aa overlap). COULD BELONG TO PROTOZOAN/CYANOBACTERIAL GLOBIN FAMILY PROTEIN. Protein product from Mb2497 detected using shotgun mass spectrometry and SWATH mass spectrometry. Mb2497 found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="GOA:P0A596" /db_xref="InterPro:IPR001486" /db_xref="InterPro:IPR009050" /db_xref="InterPro:IPR012292" /db_xref="InterPro:IPR019795" /db_xref="UniProtKB/Swiss-Prot:P0A596" BEGIN 1 MPKSFYDAVG GAKTFDAIVS RFYAQVAEDE VLRRVYPEDD LAGAEERLRM FLEQYWGGPR 61 TYSEQRGHPR LRMRHAPFRI SLIERDAWLR CMHTAVASID SETLDDEHRR ELLDYLEMAA 121 HSLVNSPF //