LOCUS       SIU01091.1               419 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 putative
            membrane protein protein.
ACCESSION   LT708304-2505
PROTEIN_ID  SIU01091.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB2476C"
                     /note="Mb2476c, -, len: 419 aa. Equivalent to Rv2449c,
                     len: 419 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 419 aa overlap). Conserved
                     hypothetical protein, highly similar to hypothetical
                     proteins e.g. P95139|Rv2953|MTCY349.37c from M.
                     tuberculosis (418 aa), FASTA scores: opt: 1829, E():
                     4.7e-103, (67.3% identity in 419 aa overlap);
                     AAK47353|MT3027 from Mycobacterium tuberculosis strain
                     CDC1551 (418 aa), FASTA score: opt: 1829, E(): 4.7e-103,
                     (67.3 identity in 419 aa overlap); Q9CD87|ML0129 from
                     Mycobacterium leprae (418 aa), FASTA scores: opt: 1727,
                     E(): 6.8e-97, (65.45% identity in 414 aa overlap); etc.
                     Protein product from Mb2476c detected using shotgun mass
                     spectrometry and SWATH mass spectrometry. Mb2476c found to
                     be expressed during exponential growth in Sauton's minimal
                     media by RNA-sequencing (TPM > 20)."
                     /db_xref="GOA:A0A1R3Y194"
                     /db_xref="InterPro:IPR005097"
                     /db_xref="InterPro:IPR036291"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3Y194"
                     /experiment="experimental evidence, no additional details
                     recorded"
BEGIN
        1 MTATPREFDI VLYGATGFVG KLTAEYLARA GGDARIALAG RSTQRVLAVR EALGESAQTW
       61 PILTADASLP STLQAMAARA QVVVTTVGPY TRYGLPLVAA CAAAGTDYAD LTGEPMFMRN
      121 SIDLYHKQAA DTGARIVHAC GFDSVPSDLS VYALYHAARE DGAGELTDTN CVVRSFKGGF
      181 SGGTIASMLE VLSTASNDPD ARRQLSDPYM LSPDRGAEPE LGPQPDLPSR RGRRLAPELA
      241 GVWTAGFIMA PTNTRIVRRS NALLDWAYGR RFRYSETMSV GSTVLAPVVS VVGGGVGNAM
      301 FGLASRYIRL LPRGLVKRVV PKPGTGPSAA ARERGYYRIE TYTTTTTGAR YLARMAQDGD
      361 PGYKATSVLL GECGLALALD RDKLSDMRGV LTPAAAMGDA LLERLPAAGV SLQTTRLAS
//