LOCUS       SIU01088.1               123 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE
            CONSERVED INTEGRAL MEMBRANE PROTEIN protein.
ACCESSION   LT708304-2502
PROTEIN_ID  SIU01088.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB2473C"
                     /note="Mb2473c, -, len: 123 aa. Equivalent to Rv2446c,
                     len: 123 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 123 aa overlap). Probable conserved
                     integral membrane protein, highly similar to Q9CBY9|ML1470
                     CONSERVED MEMBRANE PROTEIN from Mycobacterium leprae (123
                     aa), FASTA scores: opt: 468, E(): 6.7e-23, (66.65%
                     identity in 108 aa overlap). Also similar to
                     Q9L1G5|SCC88.24c PUTATIVE MEMBRANE PROTEIN from
                     Streptomyces coelicolor (118 aa), FASTA scores: opt: 130,
                     E(): 0.13, (37.2% identity in 86 aa overlap); and some
                     similarity to O06852|Y13070 hypothetical Streptomyces
                     coelicolor gene also between fpgs and ndk genes (see
                     citation below) (117 aa), FASTA scores: opt: 128, E():
                     0.17, (36.0% identity in 86 aa overlap). Mb2473c found to
                     be expressed during exponential growth in Sauton's minimal
                     media by RNA-sequencing."
                     /db_xref="GOA:A0A1R3Y174"
                     /db_xref="InterPro:IPR025327"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3Y174"
BEGIN
        1 MTDRSREPAD PWKGFSAVMA ATLILEAIVV LLAIPVVDAV GGGLRPASLG YLVGLAVLLI
       61 LLTGLQRRPW AIWVNLGAQP VLVAGFAVYP GVGFIGVLFA ALWVLIAYLR AEVRRRRDYR
      121 VSQ
//