LOCUS SIU01088.1 123 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE CONSERVED INTEGRAL MEMBRANE PROTEIN protein. ACCESSION LT708304-2502 PROTEIN_ID SIU01088.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /locus_tag="BQ2027_MB2473C" /note="Mb2473c, -, len: 123 aa. Equivalent to Rv2446c, len: 123 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 123 aa overlap). Probable conserved integral membrane protein, highly similar to Q9CBY9|ML1470 CONSERVED MEMBRANE PROTEIN from Mycobacterium leprae (123 aa), FASTA scores: opt: 468, E(): 6.7e-23, (66.65% identity in 108 aa overlap). Also similar to Q9L1G5|SCC88.24c PUTATIVE MEMBRANE PROTEIN from Streptomyces coelicolor (118 aa), FASTA scores: opt: 130, E(): 0.13, (37.2% identity in 86 aa overlap); and some similarity to O06852|Y13070 hypothetical Streptomyces coelicolor gene also between fpgs and ndk genes (see citation below) (117 aa), FASTA scores: opt: 128, E(): 0.17, (36.0% identity in 86 aa overlap). Mb2473c found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="GOA:A0A1R3Y174" /db_xref="InterPro:IPR025327" /db_xref="UniProtKB/TrEMBL:A0A1R3Y174" BEGIN 1 MTDRSREPAD PWKGFSAVMA ATLILEAIVV LLAIPVVDAV GGGLRPASLG YLVGLAVLLI 61 LLTGLQRRPW AIWVNLGAQP VLVAGFAVYP GVGFIGVLFA ALWVLIAYLR AEVRRRRDYR 121 VSQ //