LOCUS SIU01071.1 194 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 ppe family protein ppe41 protein. ACCESSION LT708304-2485 PROTEIN_ID SIU01071.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /gene="PPE41" /locus_tag="BQ2027_MB2456C" /note="Mb2456c, PPE41, len: 194 aa. Equivalent to Rv2430c, len: 194 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 194 aa overlap). Member of the Mycobacterium tuberculosis PPE family similar to others e.g. AAK46014|Rv1745|MT1745 from Mycobacterium tuberculosis (385 aa) FASTA scores: opt: 389, E(): 1.2e-17, (35.95% identity in 192 aa overlap); etc. Protein product from Mb2456c detected using SWATH mass spectrometry. Mb2456c found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="InterPro:IPR000030" /db_xref="InterPro:IPR038332" /db_xref="UniProtKB/TrEMBL:A0A1R3Y173" /experiment="experimental evidence, no additional details recorded" BEGIN 1 MHFEAYPPEV NSANIYAGPG PDSMLAAARA WRSLDVEMTA VQRSFNRTLL SLMDAWAGPV 61 VMQLMEAAKP FVRWLTDLCV QLSEVERQIH EIVRAYEWAH HDMVPLAQIY NNRAERQILI 121 DNNALGQFTA QIADLDQEYD DFWDEDGEVM RDYRLRVSDA LSKLTPWKAP PPIAHSTVLV 181 APVSPSTASS RTDT //