LOCUS SIU01065.1 291 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 Carbon monoxide oxidation accessory protein CoxD protein. ACCESSION LT708304-2479 PROTEIN_ID SIU01065.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /locus_tag="BQ2027_MB2450C" /note="Mb2450c, -, len: 291 aa. Equivalent to Rv2426c, len: 291 aa, from Mycobacterium tuberculosis strain H37Rv, (99.7% identity in 291 aa overlap). Conserved hypothetical protein, highly similar to others e.g. Q51326|ORF4 from Pseudomonas carboxydovorans (295 aa), FASTA scores: opt: 853, E(): 3.7e-43, (48.75% identity in 277 aa overlap); BAB47746|MLR0088 from Rhizobium loti (309 aa), FASTA scores: opt :809, E(): 1.5e-40, (46.5% identity in 291 aa overlap); Q9Y9R8|APE2220 from Aeropyrum pernix (297 aa), FASTA scores: opt: 763, E(): 7.4e-38, (47.1% identity in 261 aa overlap); etc. Contains PS00017 ATP/GTP-binding site motif A (P-loop). Protein product from Mb2450c detected using shotgun mass spectrometry and SWATH mass spectrometry. Mb2450c found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="GOA:A0A1R3Y1Z5" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR011704" /db_xref="InterPro:IPR027417" /db_xref="UniProtKB/TrEMBL:A0A1R3Y1Z5" BEGIN 1 MTVPARPTPL FADIADVSRR LAETGYLPDT ATATAVFLAD RLGKPLLVEG PAGVGKTELA 61 RAVAQATGSG LVRLQCYEGV DEARALYEWN HAKQILRIQA GSGDWEATKT DVLSEEFLLQ 121 RPLLTAIRRT EPTVLLIDET DKADIEIEGL LLEVLSDFAV TVPELGTLTA TRAPFVLLTS 181 NATRELSEAL KRRCLYLHID FPTPELERRI LLSRVPELPE HFAEELVRII GVLRGMQLKK 241 VPSIAETIDW GRTVLALGLD TIDDAVVAAT LGVVLKHQSD QQRATGELRL N //