LOCUS       SIU01065.1               291 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 Carbon
            monoxide oxidation accessory protein CoxD protein.
ACCESSION   LT708304-2479
PROTEIN_ID  SIU01065.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB2450C"
                     /note="Mb2450c, -, len: 291 aa. Equivalent to Rv2426c,
                     len: 291 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (99.7% identity in 291 aa overlap). Conserved hypothetical
                     protein, highly similar to others e.g. Q51326|ORF4 from
                     Pseudomonas carboxydovorans (295 aa), FASTA scores: opt:
                     853, E(): 3.7e-43, (48.75% identity in 277 aa overlap);
                     BAB47746|MLR0088 from Rhizobium loti (309 aa), FASTA
                     scores: opt :809, E(): 1.5e-40, (46.5% identity in 291 aa
                     overlap); Q9Y9R8|APE2220 from Aeropyrum pernix (297 aa),
                     FASTA scores: opt: 763, E(): 7.4e-38, (47.1% identity in
                     261 aa overlap); etc. Contains PS00017 ATP/GTP-binding
                     site motif A (P-loop). Protein product from Mb2450c
                     detected using shotgun mass spectrometry and SWATH mass
                     spectrometry. Mb2450c found to be expressed during
                     exponential growth in Sauton's minimal media by
                     RNA-sequencing."
                     /db_xref="GOA:A0A1R3Y1Z5"
                     /db_xref="InterPro:IPR003593"
                     /db_xref="InterPro:IPR011704"
                     /db_xref="InterPro:IPR027417"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3Y1Z5"
BEGIN
        1 MTVPARPTPL FADIADVSRR LAETGYLPDT ATATAVFLAD RLGKPLLVEG PAGVGKTELA
       61 RAVAQATGSG LVRLQCYEGV DEARALYEWN HAKQILRIQA GSGDWEATKT DVLSEEFLLQ
      121 RPLLTAIRRT EPTVLLIDET DKADIEIEGL LLEVLSDFAV TVPELGTLTA TRAPFVLLTS
      181 NATRELSEAL KRRCLYLHID FPTPELERRI LLSRVPELPE HFAEELVRII GVLRGMQLKK
      241 VPSIAETIDW GRTVLALGLD TIDDAVVAAT LGVVLKHQSD QQRATGELRL N
//