LOCUS SIU01055.1 280 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 DegV family protein protein. ACCESSION LT708304-2469 PROTEIN_ID SIU01055.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /locus_tag="BQ2027_MB2440C" /note="Mb2440c, -, len: 280 aa. Equivalent to Rv2417c, len: 280 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 280 aa overlap). Conserved hypothetical protein, highly similar to Q9RDL7|SCC123.07c HYPOTHETICAL 29.2 KDA PROTEIN from Streptomyces coelicolor (281 aa), FASTA scores: opt: 579, E(): 3.6e-27, (38.3% identity in 274 aa overlap). Also some similarity with DEGV proteins or hypothetical proteins from other organisms, e.g. Q9RSY3|DR1986 from Deinococcus radiodurans (281 aa), FASTA scores: opt: 393, E(): 3.4e-16, (31.0% identity in 280 aa overlap); P32436|DEGV_BACSU from Bacillus subtilis (281 aa), FASTA scores: opt: 365, E(): 1.5e-14, (27.8% identity in 284 aa overlap); BAB41937|BAB46307|SA0704|SAV0749 Conserved hypothetical protein from Staphylococcus aureus strain Mu50 and N315 (288 aa), FASTA scores: opt: 371, E(): 7e-15, (28.85% identity in 281 aa overlap); etc. Protein product from Mb2440c detected using shotgun mass spectrometry and SWATH mass spectrometry. Mb2440c found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="GOA:P67369" /db_xref="InterPro:IPR003797" /db_xref="UniProtKB/Swiss-Prot:P67369" BEGIN 1 MTVVVVTDTS CRLPADLREQ WSIRQVPLHI LLDGLDLRDG VDEIPDDIHK RHATTAGATP 61 VELSAAYQRA LADSGGDGVV AVHISSALSG TFRAAELTAA ELGPAVRVID SRSAAMGVGF 121 AALAAGRAAA AGDELDTVAR AAAAAVSRIH AFVAVARLDN LRRSGRISGA KAWLGTALAL 181 KPLLSVDDGK LVLVQRVRTV SNATAVMIDR VCQLVGDRPA ALAVHHVADP AAANDVAAAL 241 AERLPACEPA MVTAMGPVLA LHVGAGAVGV CVDVGASPPA //