LOCUS       SIU01055.1               280 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 DegV
            family protein protein.
ACCESSION   LT708304-2469
PROTEIN_ID  SIU01055.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB2440C"
                     /note="Mb2440c, -, len: 280 aa. Equivalent to Rv2417c,
                     len: 280 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 280 aa overlap). Conserved
                     hypothetical protein, highly similar to Q9RDL7|SCC123.07c
                     HYPOTHETICAL 29.2 KDA PROTEIN from Streptomyces coelicolor
                     (281 aa), FASTA scores: opt: 579, E(): 3.6e-27, (38.3%
                     identity in 274 aa overlap). Also some similarity with
                     DEGV proteins or hypothetical proteins from other
                     organisms, e.g. Q9RSY3|DR1986 from Deinococcus radiodurans
                     (281 aa), FASTA scores: opt: 393, E(): 3.4e-16, (31.0%
                     identity in 280 aa overlap); P32436|DEGV_BACSU from
                     Bacillus subtilis (281 aa), FASTA scores: opt: 365, E():
                     1.5e-14, (27.8% identity in 284 aa overlap);
                     BAB41937|BAB46307|SA0704|SAV0749 Conserved hypothetical
                     protein from Staphylococcus aureus strain Mu50 and N315
                     (288 aa), FASTA scores: opt: 371, E(): 7e-15, (28.85%
                     identity in 281 aa overlap); etc. Protein product from
                     Mb2440c detected using shotgun mass spectrometry and SWATH
                     mass spectrometry. Mb2440c found to be expressed during
                     exponential growth in Sauton's minimal media by
                     RNA-sequencing."
                     /db_xref="GOA:P67369"
                     /db_xref="InterPro:IPR003797"
                     /db_xref="UniProtKB/Swiss-Prot:P67369"
BEGIN
        1 MTVVVVTDTS CRLPADLREQ WSIRQVPLHI LLDGLDLRDG VDEIPDDIHK RHATTAGATP
       61 VELSAAYQRA LADSGGDGVV AVHISSALSG TFRAAELTAA ELGPAVRVID SRSAAMGVGF
      121 AALAAGRAAA AGDELDTVAR AAAAAVSRIH AFVAVARLDN LRRSGRISGA KAWLGTALAL
      181 KPLLSVDDGK LVLVQRVRTV SNATAVMIDR VCQLVGDRPA ALAVHHVADP AAANDVAAAL
      241 AERLPACEPA MVTAMGPVLA LHVGAGAVGV CVDVGASPPA
//