LOCUS       SIU01049.1               551 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 Protein
            containing domains DUF404, DUF407 protein.
ACCESSION   LT708304-2463
PROTEIN_ID  SIU01049.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB2434C"
                     /note="Mb2434c, -, len: 551 aa. Equivalent to Rv2411c,
                     len: 551 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 551 aa overlap). Hypothetical protein,
                     highly similar to Q49755|YO11_MYCLE|ML0605|MLCL536.05c|U19
                     37B|B1937_F1_4 HYPOTHETICAL 61.8 KDA PROTEIN from
                     Mycobacterium leprae (561 aa), FASTA scores, opt: 3163,
                     E(): 4.1e-178, (87.35% identity in 554 aa overlap). Also
                     highly similar, except in N-terminus, to others e.g.
                     Q55587|Y335_SYNY3|SLL0335 HYPOTHETICAL PROTEIN from
                     Synechocystis sp. strain PCC 6803 (481 aa), FASTA scores:
                     opt: 1620, E(): 1.2e-87, (52.8% identity in 468 aa
                     overlap); Q9I307|PA1730 HYPOTHETICAL PROTEIN from
                     Pseudomonas aeruginosa (470 aa), FASTA scores: opt: 1574,
                     E(): 5.8e-85, (52.7% identity in 467 aa overlap);
                     Q9RST1|DR2042 CONSERVED HYPOTHETICAL PROTEIN from
                     Deinococcus radiodurans (655 aa), FASTA scores: opt: 1561,
                     E(): 4.4e-84, (53.3% identity in 467 aa overlap); etc.
                     Protein product from Mb2434c detected using shotgun mass
                     spectrometry and SWATH mass spectrometry. Mb2434c found to
                     be expressed during exponential growth in Sauton's minimal
                     media by RNA-sequencing."
                     /db_xref="InterPro:IPR007302"
                     /db_xref="InterPro:IPR016450"
                     /db_xref="UniProtKB/Swiss-Prot:P65002"
BEGIN
        1 MRRVSLPNQL NETRRRSPTR GERIFGGYNT SDVYAMAFDE MFDAQGIVRG PYKGIYAELA
       61 PSDASELKAR ADALGRAFID QGITFSLSGQ ERPFPLDLVP RVISAPEWTR LERGITQRVK
      121 ALECYLDDIY GDQEILRDGV IPRRLVTSCE HFHRQAVGIV PPNGVRIHVA GIDLIRDHRG
      181 DFRVLEDNLR SPSGVSYVME NRRTMARVFP NLFATHRVRA VDDYASHLLR ALRNSAATNE
      241 ADPTVVVLTP GVYNSAYFEH SLLARQMGVE LVEGRDLFCR DNQVYMRTTE GERQVDVIYR
      301 RIDDAFLDPL QFRADSVLGV AGLVNAARAG NVVLSSAIGN GVGDDKLVYT YVPTMIEYYL
      361 HEKPLLANVE TLRCWLDDER EEVLDRIREL VLKPVEGSGG YGIVFGPEAS QAELAAVSQK
      421 IRDDPRSWIA QPMMELSTVP TRIEGTLAPR YVDLRPFAVN DGNEVWVLPG GLTRVALVEG
      481 SRVVNSSQGG GSKDTWVLAP RASAAARELG AAQIVRSLPQ PLCDPTVDAS GYEPHDQQPQ
      541 QQQQQQQQAF H
//