LOCUS SIU01049.1 551 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 Protein containing domains DUF404, DUF407 protein. ACCESSION LT708304-2463 PROTEIN_ID SIU01049.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /locus_tag="BQ2027_MB2434C" /note="Mb2434c, -, len: 551 aa. Equivalent to Rv2411c, len: 551 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 551 aa overlap). Hypothetical protein, highly similar to Q49755|YO11_MYCLE|ML0605|MLCL536.05c|U19 37B|B1937_F1_4 HYPOTHETICAL 61.8 KDA PROTEIN from Mycobacterium leprae (561 aa), FASTA scores, opt: 3163, E(): 4.1e-178, (87.35% identity in 554 aa overlap). Also highly similar, except in N-terminus, to others e.g. Q55587|Y335_SYNY3|SLL0335 HYPOTHETICAL PROTEIN from Synechocystis sp. strain PCC 6803 (481 aa), FASTA scores: opt: 1620, E(): 1.2e-87, (52.8% identity in 468 aa overlap); Q9I307|PA1730 HYPOTHETICAL PROTEIN from Pseudomonas aeruginosa (470 aa), FASTA scores: opt: 1574, E(): 5.8e-85, (52.7% identity in 467 aa overlap); Q9RST1|DR2042 CONSERVED HYPOTHETICAL PROTEIN from Deinococcus radiodurans (655 aa), FASTA scores: opt: 1561, E(): 4.4e-84, (53.3% identity in 467 aa overlap); etc. Protein product from Mb2434c detected using shotgun mass spectrometry and SWATH mass spectrometry. Mb2434c found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="InterPro:IPR007302" /db_xref="InterPro:IPR016450" /db_xref="UniProtKB/Swiss-Prot:P65002" BEGIN 1 MRRVSLPNQL NETRRRSPTR GERIFGGYNT SDVYAMAFDE MFDAQGIVRG PYKGIYAELA 61 PSDASELKAR ADALGRAFID QGITFSLSGQ ERPFPLDLVP RVISAPEWTR LERGITQRVK 121 ALECYLDDIY GDQEILRDGV IPRRLVTSCE HFHRQAVGIV PPNGVRIHVA GIDLIRDHRG 181 DFRVLEDNLR SPSGVSYVME NRRTMARVFP NLFATHRVRA VDDYASHLLR ALRNSAATNE 241 ADPTVVVLTP GVYNSAYFEH SLLARQMGVE LVEGRDLFCR DNQVYMRTTE GERQVDVIYR 301 RIDDAFLDPL QFRADSVLGV AGLVNAARAG NVVLSSAIGN GVGDDKLVYT YVPTMIEYYL 361 HEKPLLANVE TLRCWLDDER EEVLDRIREL VLKPVEGSGG YGIVFGPEAS QAELAAVSQK 421 IRDDPRSWIA QPMMELSTVP TRIEGTLAPR YVDLRPFAVN DGNEVWVLPG GLTRVALVEG 481 SRVVNSSQGG GSKDTWVLAP RASAAARELG AAQIVRSLPQ PLCDPTVDAS GYEPHDQQPQ 541 QQQQQQQQAF H //