LOCUS       SIU01037.1               356 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE
            SULFATE-BINDING LIPOPROTEIN SUBI protein.
ACCESSION   LT708304-2451
PROTEIN_ID  SIU01037.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="subI"
                     /locus_tag="BQ2027_MB2422C"
                     /note="Mb2422c, subI, len: 356 aa. Equivalent to Rv2400c,
                     len: 356 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 356 aa overlap). Probable subI,
                     sulfate-binding lipoprotein component of sulfate transport
                     system (see citations below), equivalent to
                     Q9CCN3|SUBI|ML0615 (alias Q49748|B1937_F1_11, 358 aa)
                     PUTATIVE SULPHATE-BINDING PROTEIN from Mycobacterium
                     leprae (348 aa), FASTA scores: opt: 1775, E(): 2.3e-102,
                     (76.45% identity in 340 aa overlap). Also similar to
                     others and other substrate-binding proteins e.g.
                     P27366|SUBI_SYNP7|SBPA SULFATE-BINDING PROTEIN PRECURSOR
                     from Synechococcus sp. strain PCC 7942 (Anacystis nidulans
                     R2) (350 aa), FASTA scores: opt: 703, E(): 4.6e-36, (35.6%
                     identity in 351 aa overlap); Q9I6K7|SBP|PA0283
                     SULFATE-BINDING PROTEIN PRECURSOR from Pseudomonas
                     aeruginosa (332 aa), FASTA scores: opt: 591, E(): 3.7e-29,
                     (36.9% identity in 317 aa overlap); CAC49112|SMB21133
                     PUTATIVE SULFATE UPTAKE ABC TRANSPORTER PERIPLASMIC
                     SOLUTE-BINDING PROTEIN PRECURSOR from Rhizobium meliloti
                     (Sinorhizobium meliloti) (341 aa), FASTA scores: opt: 569,
                     E(): 8.8e-28, (36.15% identity in 321 aa overlap); etc.
                     BELONGS TO THE PROKARYOTIC SULFATE BINDING PROTEIN FAMILY.
                     Protein product from Mb2422c detected using shotgun mass
                     spectrometry and SWATH mass spectrometry. Mb2422c found to
                     be expressed during exponential growth in Sauton's minimal
                     media by RNA-sequencing."
                     /db_xref="GOA:A0A1R3Y1G6"
                     /db_xref="InterPro:IPR005669"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3Y1G6"
                     /experiment="experimental evidence, no additional details
                     recorded"
BEGIN
        1 MLSLTLSEAS CIASASRWRH IIPAGVVCAL IAGIGVGCHG GPSDVVGRAG PDRAHTSITL
       61 VAYAVPEPGW SAVIPAFNAS EQGRGVQVIT SYGASADQSR GVADGKPADL VNFSVEPDIA
      121 RLVKAGKVDK DWDADATKGI PFGSVVTFVV RAGNPKNIRD WDDLLRPGIE VITPSPLSSG
      181 SAKWNLLAPY AAKSDGGRNN QAGIDFVNTL VNEHVKLRPG SGREATDVFV QGSGDVLISY
      241 ENEAIATERA GKPVQHVTPP QTFKIENPLA VVATSTHLGA ATAFRNFQYT VQAQKLWAQA
      301 GFRPVDPAVA ADFADLFPVP AKLWTIADLG GWGSVDPQLF DKATGSITKI YLRATG
//