LOCUS       SIU01006.1               382 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE
            CHAPERONE PROTEIN DNAJ2 protein.
ACCESSION   LT708304-2420
PROTEIN_ID  SIU01006.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="dnaJ2"
                     /locus_tag="BQ2027_MB2394C"
                     /note="Mb2394c, dnaJ2, len: 382 aa. Equivalent to Rv2373c,
                     len: 382 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 382 aa overlap). Probable dnaJ2,
                     chaperone protein, equivalent to
                     Q49762|DNJ2_MYCLE|ML0625|B1937_F2_56 CHAPERONE PROTEIN
                     from Mycobacterium leprae (378 aa), FASTA scores: opt:
                     2301, E(): 1.7e-120, (87.5% identity in 382 aa overlap).
                     Also highly similar to OTHER CHAPERONE PROTEINS DNAJ/DNAJ2
                     e.g. Q9RDD7|DNJ2_STRCO|SCC77.21c from Streptomyces
                     coelicolor (378 aa), FASTA scores: opt: 1456, E():
                     1.2e-73, (54.8% identity in 385 aa overlap);
                     O52164|DNJ2_STRAL from Streptomyces albus (379 aa) FASTA
                     scores: opt: 1378, E(): 2.6e-69, (52.2% identity in 385 aa
                     overlap); Q9S5A3|DNAJ_LISMO from Listeria monocytogenes
                     (377 aa), FASTA scores: opt: 1013, E(): 4.6e-49, (41.3%
                     identity in 385 aa overlap); etc. Also similar to
                     Rv0352|MTCY13E10.12 from Mycobacterium tuberculosis.
                     Contains 1 J domain and 1 CR domain. BELONGS TO THE DNAJ
                     FAMILY. Protein product from Mb2394c detected using
                     shotgun mass spectrometry and SWATH mass spectrometry.
                     Mb2394c found to be expressed during exponential growth in
                     Sauton's minimal media by RNA-sequencing."
                     /db_xref="GOA:P63967"
                     /db_xref="InterPro:IPR001305"
                     /db_xref="InterPro:IPR001623"
                     /db_xref="InterPro:IPR002939"
                     /db_xref="InterPro:IPR008971"
                     /db_xref="InterPro:IPR012724"
                     /db_xref="InterPro:IPR036410"
                     /db_xref="InterPro:IPR036869"
                     /db_xref="UniProtKB/Swiss-Prot:P63967"
                     /experiment="experimental evidence, no additional details
                     recorded"
BEGIN
        1 MARDYYGLLG VSKNASDADI KRAYRKLARE LHPDVNPDEA AQAKFKEISV AYEVLSDPDK
       61 RRIVDLGGDP LESAAAGGNG FGGFGGLGDV FEAFFGGGFG GGAASRGPIG RVRPGSDSLL
      121 RMRLDLEECA TGVTKQVTVD TAVLCDRCQG KGTNGDSVPI PCDTCGGRGE VQTVQRSLLG
      181 QMLTSRPCPT CRGVGVVIPD PCQQCMGDGR IRARREISVK IPAGVGDGMR VRLAAQGEVG
      241 PGGGPAGDLY VEVHEQAHDV FVREGDHLHC TVSVPMVDAA LGVTVTVDAI LDGLSEITIP
      301 PGTQPGSVIT LRGRGMPHLR SNTRGDLHVH VEVVVPTRLD HQDIELLREL KGRRDREVAE
      361 VRSTHAAAGG LFSRLRETFT GR
//