LOCUS SIU01000.1 182 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 Metal- dependent hydrolase YbeY, involved in rRNA and/or ribosome maturation and assembly protein. ACCESSION LT708304-2414 PROTEIN_ID SIU01000.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /gene="ybeY" /locus_tag="BQ2027_MB2388C" /note="Mb2388c, -, len: 182 aa. Equivalent to Rv2367c, len: 182 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 182 aa overlap). Conserved hypothetical protein, equivalent to Q49752|YN67_MYCLE|ML0628|B1937_F1_21 HYPOTHETICAL 19.8 KDA PROTEIN from Mycobacterium leprae (178 aa), FASTA scores: opt: 1051, E(): 2e-59, (89.1% identity in 175 aa overlap). Also highly similar to others e.g. Q9L2L4|SCC117.06 CONSERVED HYPOTHETICAL PROTEIN from Streptomyces coelicolor (165 aa), FASTA scores: opt: 599, E(): 6e-31, (56.5% identity in 154 aa overlap); Q9KD56|BH1363 HYPOTHETICAL PROTEIN from Bacillus halodurans (159 aa), FASTA scores: opt: 311, E(): 8.3e-13, (45.05% identity in 111 aa overlap); etc. Protein product from Mb2388c detected using shotgun mass spectrometry. Mb2388c found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing (TPM > 20)." /db_xref="GOA:P67135" /db_xref="InterPro:IPR002036" /db_xref="InterPro:IPR020549" /db_xref="InterPro:IPR023091" /db_xref="UniProtKB/Swiss-Prot:P67135" BEGIN 1 MREHLMSIEV ANESGIDVSE AELVSVARFV IAKMDVNPCA ELSMLLLDTA AMADLHMRWM 61 DLPGPTDVMS FPMDELEPGG RPDAPEPGPS MLGDIVLCPE FAAEQAAAAG HSLGHELALL 121 TIHGVLHLLG YDHAEPDEEK EMFALQDRLL EEWVADQVEA YQHDRQDEKD RRLLDKSRYF 181 DL //