LOCUS       SIU01000.1               182 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 Metal-
            dependent hydrolase YbeY, involved in rRNA and/or ribosome
            maturation and assembly protein.
ACCESSION   LT708304-2414
PROTEIN_ID  SIU01000.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="ybeY"
                     /locus_tag="BQ2027_MB2388C"
                     /note="Mb2388c, -, len: 182 aa. Equivalent to Rv2367c,
                     len: 182 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 182 aa overlap). Conserved
                     hypothetical protein, equivalent to
                     Q49752|YN67_MYCLE|ML0628|B1937_F1_21 HYPOTHETICAL 19.8 KDA
                     PROTEIN from Mycobacterium leprae (178 aa), FASTA scores:
                     opt: 1051, E(): 2e-59, (89.1% identity in 175 aa overlap).
                     Also highly similar to others e.g. Q9L2L4|SCC117.06
                     CONSERVED HYPOTHETICAL PROTEIN from Streptomyces
                     coelicolor (165 aa), FASTA scores: opt: 599, E(): 6e-31,
                     (56.5% identity in 154 aa overlap); Q9KD56|BH1363
                     HYPOTHETICAL PROTEIN from Bacillus halodurans (159 aa),
                     FASTA scores: opt: 311, E(): 8.3e-13, (45.05% identity in
                     111 aa overlap); etc. Protein product from Mb2388c
                     detected using shotgun mass spectrometry. Mb2388c found to
                     be expressed during exponential growth in Sauton's minimal
                     media by RNA-sequencing (TPM > 20)."
                     /db_xref="GOA:P67135"
                     /db_xref="InterPro:IPR002036"
                     /db_xref="InterPro:IPR020549"
                     /db_xref="InterPro:IPR023091"
                     /db_xref="UniProtKB/Swiss-Prot:P67135"
BEGIN
        1 MREHLMSIEV ANESGIDVSE AELVSVARFV IAKMDVNPCA ELSMLLLDTA AMADLHMRWM
       61 DLPGPTDVMS FPMDELEPGG RPDAPEPGPS MLGDIVLCPE FAAEQAAAAG HSLGHELALL
      121 TIHGVLHLLG YDHAEPDEEK EMFALQDRLL EEWVADQVEA YQHDRQDEKD RRLLDKSRYF
      181 DL
//