LOCUS       SIU00975.1               229 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE
            SERINE ACETYLTRANSFERASE CYSE (SAT) protein.
ACCESSION   LT708304-2389
PROTEIN_ID  SIU00975.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="cysE"
                     /locus_tag="BQ2027_MB2363"
                     /note="Mb2363, -, len: 229 aa. Equivalent to Rv2335, len:
                     229 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 229 aa overlap). Probable cysE, serine
                     acetyltransferase (EC 2.3.1.30), equivalent to
                     O32979|CYSE|ML0838 SERINE ACETYLTRANSFERASE from
                     Mycobacterium leprae (227 aa), FASTA scores: opt: 1152,
                     E(): 9.6e-62, (76.4% identity in 229 aa overlap). Also
                     highly similar, except in C-terminal part, to others e.g.
                     Q9HXI6|CYSE|PA3816 O-ACETYLSERINE SYNTHASE from
                     Pseudomonas aeruginosa (258 aa), FASTA scores: opt: 737,
                     E(): 6e-37, (61.3% identity in 168 aa overlap);
                     P23145|NIFP_AZOCH PROBABLE SERINE ACETYLTRANSFERASE from
                     Azotobacter chroococcum mcd 1 (269 aa), FASTA scores: opt:
                     718, E(): 8.4e-36, (55.45% identity in 220 aa overlap);
                     Q06750|CYSE_BACSU SERINE ACETYLTRANSFERASE from Bacillus
                     subtilis (217 aa), FASTA scores: opt: 640, E(): 3.1e-31,
                     (48.0% identity in 200 aa overlap); etc. Contains PS00101
                     Bacterial hexapeptide-repeat containing-transferases
                     signature. BELONGS TO THE CYSE/LACA/LPXA/NODL FAMILY OF
                     ACETYLTRANSFERASES. COMPOSED OF MULTIPLE REPEATS OF
                     [LIV]-G-X(4). Protein product from Mb2363 detected using
                     shotgun mass spectrometry and SWATH mass spectrometry.
                     Mb2363 found to be expressed during exponential growth in
                     Sauton's minimal media by RNA-sequencing."
                     /db_xref="GOA:A0A1R3Y1P8"
                     /db_xref="InterPro:IPR001451"
                     /db_xref="InterPro:IPR005881"
                     /db_xref="InterPro:IPR011004"
                     /db_xref="InterPro:IPR018357"
                     /db_xref="InterPro:IPR042122"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3Y1P8"
BEGIN
        1 MLTAMRGDIR AARERDPAAP TALEVIFCYP GVHAVWGHRL AHWLWQRGAR LLARAAAEFT
       61 RILTGVDIHP GAVIGARVFI DHATGVVIGE TAEVGDDVTI YHGVTLGGSG MVGGKRHPTV
      121 GDRVIIGAGA KVLGPIKIGE DSRIGANAVV VKPVPPSAVV VGVPGQVIGQ SQPSPGGPFD
      181 WRLPDLVGAS LDSLLTRVAR LEALGGGPQA AGVIRPPEAG IWHGEDFSI
//