LOCUS SIU00975.1 229 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE SERINE ACETYLTRANSFERASE CYSE (SAT) protein. ACCESSION LT708304-2389 PROTEIN_ID SIU00975.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /gene="cysE" /locus_tag="BQ2027_MB2363" /note="Mb2363, -, len: 229 aa. Equivalent to Rv2335, len: 229 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 229 aa overlap). Probable cysE, serine acetyltransferase (EC 2.3.1.30), equivalent to O32979|CYSE|ML0838 SERINE ACETYLTRANSFERASE from Mycobacterium leprae (227 aa), FASTA scores: opt: 1152, E(): 9.6e-62, (76.4% identity in 229 aa overlap). Also highly similar, except in C-terminal part, to others e.g. Q9HXI6|CYSE|PA3816 O-ACETYLSERINE SYNTHASE from Pseudomonas aeruginosa (258 aa), FASTA scores: opt: 737, E(): 6e-37, (61.3% identity in 168 aa overlap); P23145|NIFP_AZOCH PROBABLE SERINE ACETYLTRANSFERASE from Azotobacter chroococcum mcd 1 (269 aa), FASTA scores: opt: 718, E(): 8.4e-36, (55.45% identity in 220 aa overlap); Q06750|CYSE_BACSU SERINE ACETYLTRANSFERASE from Bacillus subtilis (217 aa), FASTA scores: opt: 640, E(): 3.1e-31, (48.0% identity in 200 aa overlap); etc. Contains PS00101 Bacterial hexapeptide-repeat containing-transferases signature. BELONGS TO THE CYSE/LACA/LPXA/NODL FAMILY OF ACETYLTRANSFERASES. COMPOSED OF MULTIPLE REPEATS OF [LIV]-G-X(4). Protein product from Mb2363 detected using shotgun mass spectrometry and SWATH mass spectrometry. Mb2363 found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="GOA:A0A1R3Y1P8" /db_xref="InterPro:IPR001451" /db_xref="InterPro:IPR005881" /db_xref="InterPro:IPR011004" /db_xref="InterPro:IPR018357" /db_xref="InterPro:IPR042122" /db_xref="UniProtKB/TrEMBL:A0A1R3Y1P8" BEGIN 1 MLTAMRGDIR AARERDPAAP TALEVIFCYP GVHAVWGHRL AHWLWQRGAR LLARAAAEFT 61 RILTGVDIHP GAVIGARVFI DHATGVVIGE TAEVGDDVTI YHGVTLGGSG MVGGKRHPTV 121 GDRVIIGAGA KVLGPIKIGE DSRIGANAVV VKPVPPSAVV VGVPGQVIGQ SQPSPGGPFD 181 WRLPDLVGAS LDSLLTRVAR LEALGGGPQA AGVIRPPEAG IWHGEDFSI //