LOCUS       SIU00936.1                80 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 conserved
            protein protein.
ACCESSION   LT708304-2350
PROTEIN_ID  SIU00936.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB2324"
                     /note="Mb2324, -, len: 80 aa. Equivalent to Rv2302, len:
                     80 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 80 aa overlap). Conserved hypothetical
                     protein, highly similar to others:
                     O53766|AL021942|Rv0569|MTV039.07 HYPOTHETICAL 9.5 KDA
                     PROTEIN from Mycobacterium tuberculosis (88 aa), FASTA
                     scores: opt: 300, E(): 1.4e-14, (61.85% identity in 76 aa
                     overlap); O88049|SCI35.11 HYPOTHETICAL 7.1 KDA PROTEIN
                     from Streptomyces coelicolor (64 aa), FASTA scores: opt:
                     169, E(): 1.5e-05, (46.55% identity in 58 aa overlap) (has
                     its C-terminus shorter); Q9XCD1 HYPOTHETICAL 12.0 KDA
                     PROTEIN (FRAGMENT) from Thermomonospora fusca (106 aa),
                     FASTA scores: opt: 126, E(): 0.023, (50.0% identity in 34
                     aa overlap) (similarity in part for this one). Also weakly
                     similar to U650M|G699303|Q50105 HYPOTHETICAL 5.7 KDA
                     PROTEIN from Mycobacterium leprae (53 aa), FASTA scores:
                     opt: 89, E(): 0.66, (45.5% identity in 33 aa overlap); and
                     weakly similar to N-terminus of Q9RIZ1|SCJ1.23c putative
                     DNA-binding protein from Streptomyces coelicolor (323 aa),
                     FASTA scores: opt: 182, E(): 7.3e-06, (42.25% identity in
                     71 aa overlap). Protein product from Mb2324 detected using
                     shotgun mass spectrometry and SWATH mass spectrometry.
                     Mb2324 found to be expressed during exponential growth in
                     Sauton's minimal media by RNA-sequencing."
                     /db_xref="InterPro:IPR015035"
                     /db_xref="UniProtKB/Swiss-Prot:P64984"
BEGIN
        1 MHAKVGDYLV VKGTTTERHD QHAEIIEVRS ADGSPPYVVR WLVNGHETTV YPGSDAVVVT
       61 ATEHAEAEKR AAARAGHAAT
//