LOCUS SIU00936.1 80 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 conserved protein protein. ACCESSION LT708304-2350 PROTEIN_ID SIU00936.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /locus_tag="BQ2027_MB2324" /note="Mb2324, -, len: 80 aa. Equivalent to Rv2302, len: 80 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 80 aa overlap). Conserved hypothetical protein, highly similar to others: O53766|AL021942|Rv0569|MTV039.07 HYPOTHETICAL 9.5 KDA PROTEIN from Mycobacterium tuberculosis (88 aa), FASTA scores: opt: 300, E(): 1.4e-14, (61.85% identity in 76 aa overlap); O88049|SCI35.11 HYPOTHETICAL 7.1 KDA PROTEIN from Streptomyces coelicolor (64 aa), FASTA scores: opt: 169, E(): 1.5e-05, (46.55% identity in 58 aa overlap) (has its C-terminus shorter); Q9XCD1 HYPOTHETICAL 12.0 KDA PROTEIN (FRAGMENT) from Thermomonospora fusca (106 aa), FASTA scores: opt: 126, E(): 0.023, (50.0% identity in 34 aa overlap) (similarity in part for this one). Also weakly similar to U650M|G699303|Q50105 HYPOTHETICAL 5.7 KDA PROTEIN from Mycobacterium leprae (53 aa), FASTA scores: opt: 89, E(): 0.66, (45.5% identity in 33 aa overlap); and weakly similar to N-terminus of Q9RIZ1|SCJ1.23c putative DNA-binding protein from Streptomyces coelicolor (323 aa), FASTA scores: opt: 182, E(): 7.3e-06, (42.25% identity in 71 aa overlap). Protein product from Mb2324 detected using shotgun mass spectrometry and SWATH mass spectrometry. Mb2324 found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="InterPro:IPR015035" /db_xref="UniProtKB/Swiss-Prot:P64984" BEGIN 1 MHAKVGDYLV VKGTTTERHD QHAEIIEVRS ADGSPPYVVR WLVNGHETTV YPGSDAVVVT 61 ATEHAEAEKR AAARAGHAAT //