LOCUS       SIU00934.1               310 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 MBL-
            fold metallo-hydrolase superfamily protein.
ACCESSION   LT708304-2348
PROTEIN_ID  SIU00934.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB2322C"
                     /note="Mb2322c, -, len: 310 aa. Equivalent to Rv2300c,
                     len: 310 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 310 aa overlap). Conserved
                     hypothetical protein, similar to others e.g. Q9RXY2|DR0172
                     CONSERVED HYPOTHETICAL PROTEIN from Deinococcus
                     radiodurans (271 aa), FASTA scores: opt: 306, E():
                     1.3e-12, (34.6% identity in 229 aa overlap); Q9HZH1|PA3037
                     HYPOTHETICAL PROTEIN from Pseudomonas aeruginosa (288 aa),
                     FASTA scores: opt: 248, E(): 7.9e-09, (31.5% identity in
                     238 aa overlap); Q9PDL8|XF1361 HYPOTHETICAL PROTEIN from
                     Xylella fastidiosa (279 aa), FASTA scores: opt: 236, E():
                     4.6e-08, (29.7% identity in 249 aa overlap);
                     U70053|XCU70053_3 GumP PROTEIN from Xanthomonas campestris
                     (282 aa), FASTA scores: opt: 222, E(): 3.7e-07, (30.1%
                     identity in 248 aa overlap); etc. Mb2322c found to be
                     expressed during exponential growth in Sauton's minimal
                     media by RNA-sequencing."
                     /db_xref="GOA:P64982"
                     /db_xref="InterPro:IPR001279"
                     /db_xref="InterPro:IPR036866"
                     /db_xref="UniProtKB/Swiss-Prot:P64982"
BEGIN
        1 MVATRGRPCP TNFSRPQRPR VAGNGTKSQR CRGRLTTSML GVAPEAKGPP VKVHHLNCGT
       61 MNAFGIALLC HVLLVETDDG LVLVDTGFGI QDCLDPGRVG LFRHVLRPAF LQAETAARQI
      121 EQLGYRTSDV RHIVLTHFDF DHIGGIADFP EAHLHVTAAE ARGAIHAPSL RERLRYRRGQ
      181 WAHGPKLVEH GPDGEPWRGF ASAKPLDSIG TGVVLVPMPG HTRGHAAVAV DAGHRWVLHC
      241 GDAFYHRGTL DGRFRVPFVM RAEEKLLSYN RNQLRDNQAR IVELHRRHDP DLLIVCAHDP
      301 DLYQLARDTA
//