LOCUS SIU00934.1 310 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 MBL- fold metallo-hydrolase superfamily protein. ACCESSION LT708304-2348 PROTEIN_ID SIU00934.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /locus_tag="BQ2027_MB2322C" /note="Mb2322c, -, len: 310 aa. Equivalent to Rv2300c, len: 310 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 310 aa overlap). Conserved hypothetical protein, similar to others e.g. Q9RXY2|DR0172 CONSERVED HYPOTHETICAL PROTEIN from Deinococcus radiodurans (271 aa), FASTA scores: opt: 306, E(): 1.3e-12, (34.6% identity in 229 aa overlap); Q9HZH1|PA3037 HYPOTHETICAL PROTEIN from Pseudomonas aeruginosa (288 aa), FASTA scores: opt: 248, E(): 7.9e-09, (31.5% identity in 238 aa overlap); Q9PDL8|XF1361 HYPOTHETICAL PROTEIN from Xylella fastidiosa (279 aa), FASTA scores: opt: 236, E(): 4.6e-08, (29.7% identity in 249 aa overlap); U70053|XCU70053_3 GumP PROTEIN from Xanthomonas campestris (282 aa), FASTA scores: opt: 222, E(): 3.7e-07, (30.1% identity in 248 aa overlap); etc. Mb2322c found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="GOA:P64982" /db_xref="InterPro:IPR001279" /db_xref="InterPro:IPR036866" /db_xref="UniProtKB/Swiss-Prot:P64982" BEGIN 1 MVATRGRPCP TNFSRPQRPR VAGNGTKSQR CRGRLTTSML GVAPEAKGPP VKVHHLNCGT 61 MNAFGIALLC HVLLVETDDG LVLVDTGFGI QDCLDPGRVG LFRHVLRPAF LQAETAARQI 121 EQLGYRTSDV RHIVLTHFDF DHIGGIADFP EAHLHVTAAE ARGAIHAPSL RERLRYRRGQ 181 WAHGPKLVEH GPDGEPWRGF ASAKPLDSIG TGVVLVPMPG HTRGHAAVAV DAGHRWVLHC 241 GDAFYHRGTL DGRFRVPFVM RAEEKLLSYN RNQLRDNQAR IVELHRRHDP DLLIVCAHDP 301 DLYQLARDTA //