LOCUS       SIU00910.1               289 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 Cyclo(
            L-tyrosyl-L-tyrosyl) synthase (EC protein.
ACCESSION   LT708304-2324
PROTEIN_ID  SIU00910.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB2298"
                     /EC_number="2.3.2.21"
                     /note="Mb2298, -, len: 289 aa. Equivalent to Rv2275, len:
                     289 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 289 aa overlap). Conserved
                     hypothetical protein. Some similarity to Bacillus subtilis
                     sp|O34351|O34351 YVMC (248 aa), FASTA score: opt: 280,
                     E(): 2.7e -11; 28.2% identity in 227 aa overlap,Mb2298
                     found to be expressed during exponential growth in
                     Sauton's minimal media by RNA-sequencing (TPM > 20)."
                     /db_xref="GOA:A0A1R3Y0S3"
                     /db_xref="InterPro:IPR030903"
                     /db_xref="InterPro:IPR038622"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3Y0S3"
                     /experiment="experimental evidence, no additional details
                     recorded"
BEGIN
        1 MSYVAAEPGV LISPTDDLQS PRSAPAAHDE NADGITGGTR DDSAPNSRFQ LGRRIPEATA
       61 QEGFLVRPFT QQCQIIHTEG DHAVIGVSPG NSYFSRQRLR DLGLWGLTNF DRVDFVYTDV
      121 HVAESYEALG DSAIEARRKA VKNIRGVRAK ITTTVNELDP AGARLCVRPM SEFQSNEAYR
      181 ELHADLLTRL KDDEDLRAVC QDLVRRFLST KVGPRQGATA TQEQVCMDYI CAEAPLFLDT
      241 PAILGVPSSL NCYHQSLPLA EMLYARGSGL RASRNQGHAI VTPDGSPAE
//