LOCUS       SIU00899.1               409 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 Possible
            conserved integral membrane protein protein.
ACCESSION   LT708304-2313
PROTEIN_ID  SIU00899.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB2288"
                     /note="Mb2288, -, len: 409 aa. Equivalent to Rv2265, len:
                     409 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 409 aa overlap). Possible conserved
                     integral membrane protein, with some similarity to others
                     e.g. M. thermoauto. sp|O26855|O26855 CONSERVED PROTEIN
                     (383 aa), FASTA score: opt: 898 z-score: 1023.5 E(): 0;
                     38.0% identity in 384 aa overlap; Q58713 HYPOTHETICAL 44.1
                     KD PROTEIN 1 317 (398 aa), FASTA scores, opt: 305 E():
                     1.2e-11; 22.8% identity in 382 aa overlap; also KGTP_ECOLI
                     P17448 alpha-ketoglutarate permease (432 aa), FASTA
                     scores, opt: 156, E(): 0.006, (24.8% identity in 416 aa
                     overlap) Protein product from Mb2288 detected using SWATH
                     mass spectrometry."
                     /db_xref="GOA:P64962"
                     /db_xref="InterPro:IPR011701"
                     /db_xref="InterPro:IPR036259"
                     /db_xref="UniProtKB/Swiss-Prot:P64962"
BEGIN
        1 MGANGDVALS RIGATRPALS AWRFVTVFGV VGLLADVVYE GARSITGPLL ASLGATGLVV
       61 GVVTGVGEAA ALGLRLVSGP LADRSRRFWA WTIAGYTLTV VTVPLLGIAG ALWVACALVI
      121 AERVGKAVRG PAKDTLLSHA ASVTGRGRGF AVHEALDQVG AMIGPLTVAG MLAITGNAYA
      181 PALGVLTLPG GAALALLLWL QRRVPRPESY EDCPVVLGNP SAPRPWALPA QFWLYCGFTA
      241 ITMLGFGTFG LLSFHMVSHG VLAAAMVPVV YAAAMAADAL TALASGFSYD RYGAKTLAVL
      301 PILSILVVLF AFTDNVTMVV IGTLVWGAAV GIQESTLRGV VADLVASPRR ASAYGVFAAG
      361 LGAATAGGGA LIGWLYDISI GTLVVVVIAL ELMALVMMFA IRLPRVAPS
//