LOCUS SIU00899.1 409 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 Possible conserved integral membrane protein protein. ACCESSION LT708304-2313 PROTEIN_ID SIU00899.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /locus_tag="BQ2027_MB2288" /note="Mb2288, -, len: 409 aa. Equivalent to Rv2265, len: 409 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 409 aa overlap). Possible conserved integral membrane protein, with some similarity to others e.g. M. thermoauto. sp|O26855|O26855 CONSERVED PROTEIN (383 aa), FASTA score: opt: 898 z-score: 1023.5 E(): 0; 38.0% identity in 384 aa overlap; Q58713 HYPOTHETICAL 44.1 KD PROTEIN 1 317 (398 aa), FASTA scores, opt: 305 E(): 1.2e-11; 22.8% identity in 382 aa overlap; also KGTP_ECOLI P17448 alpha-ketoglutarate permease (432 aa), FASTA scores, opt: 156, E(): 0.006, (24.8% identity in 416 aa overlap) Protein product from Mb2288 detected using SWATH mass spectrometry." /db_xref="GOA:P64962" /db_xref="InterPro:IPR011701" /db_xref="InterPro:IPR036259" /db_xref="UniProtKB/Swiss-Prot:P64962" BEGIN 1 MGANGDVALS RIGATRPALS AWRFVTVFGV VGLLADVVYE GARSITGPLL ASLGATGLVV 61 GVVTGVGEAA ALGLRLVSGP LADRSRRFWA WTIAGYTLTV VTVPLLGIAG ALWVACALVI 121 AERVGKAVRG PAKDTLLSHA ASVTGRGRGF AVHEALDQVG AMIGPLTVAG MLAITGNAYA 181 PALGVLTLPG GAALALLLWL QRRVPRPESY EDCPVVLGNP SAPRPWALPA QFWLYCGFTA 241 ITMLGFGTFG LLSFHMVSHG VLAAAMVPVV YAAAMAADAL TALASGFSYD RYGAKTLAVL 301 PILSILVVLF AFTDNVTMVV IGTLVWGAAV GIQESTLRGV VADLVASPRR ASAYGVFAAG 361 LGAATAGGGA LIGWLYDISI GTLVVVVIAL ELMALVMMFA IRLPRVAPS //