LOCUS SIU00893.1 353 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 Possible transcriptional regulatory protein protein. ACCESSION LT708304-2307 PROTEIN_ID SIU00893.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /locus_tag="BQ2027_MB2282C" /note="Mb2282c, -, len: 353 aa. Equivalent to Rv2258c, len:353 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 353 aa overlap). Possible transcriptional regulatory protein, similar to several hypothetical proteins from C. elegans. FASTA scores: sptr|O01593|O01593 CODED FOR BY C. ELEGANS CDNA YK102 F (365 aa) opt: 577, E(): 6.4e-31; (30.5% identity in 341 aa overlap). Contains possible helix-turn helix motif at aa 47-68 (+3.65 SD) Protein product from Mb2282c detected using shotgun mass spectrometry and SWATH mass spectrometry. Mb2282c found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="InterPro:IPR025714" /db_xref="InterPro:IPR029063" /db_xref="UniProtKB/TrEMBL:A0A1R3Y0N3" BEGIN 1 MSGALETTEE FGNRFVAAID SAGLAILVSV GHQTGLLDTM AGLPPATSME IAEAAGLEER 61 YVREWLGGMT TGQIVEYDAG SSTYSLPAHR AGMLTRAAGP DNLAVIAQFV SLLGEVEQKV 121 IRCFREGGGV PYSEYPRFHK LMAEMSGMVF DAALIDVVLP LVDGLPDRLR SGADVADFGC 181 GSGRAVKLMA QAFGASRFTG IDFSDEAVAA GTEEAARLGL ANATFERHDL AELDKVGAYD 241 VITVFDAIHD QAQPARVLQN IYRALRPGGV LLMVDIKASS QLEDNVGVPL STYLYTTSLM 301 HCMTVSLALD GAGLGTVWGR QLATSMLADA GFTDVTVAEI ESDVLNNYYI ARK //