LOCUS       SIU00893.1               353 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 Possible
            transcriptional regulatory protein protein.
ACCESSION   LT708304-2307
PROTEIN_ID  SIU00893.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB2282C"
                     /note="Mb2282c, -, len: 353 aa. Equivalent to Rv2258c,
                     len:353 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 353 aa overlap). Possible
                     transcriptional regulatory protein, similar to several
                     hypothetical proteins from C. elegans. FASTA scores:
                     sptr|O01593|O01593 CODED FOR BY C. ELEGANS CDNA YK102 F
                     (365 aa) opt: 577, E(): 6.4e-31; (30.5% identity in 341 aa
                     overlap). Contains possible helix-turn helix motif at aa
                     47-68 (+3.65 SD) Protein product from Mb2282c detected
                     using shotgun mass spectrometry and SWATH mass
                     spectrometry. Mb2282c found to be expressed during
                     exponential growth in Sauton's minimal media by
                     RNA-sequencing."
                     /db_xref="InterPro:IPR025714"
                     /db_xref="InterPro:IPR029063"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3Y0N3"
BEGIN
        1 MSGALETTEE FGNRFVAAID SAGLAILVSV GHQTGLLDTM AGLPPATSME IAEAAGLEER
       61 YVREWLGGMT TGQIVEYDAG SSTYSLPAHR AGMLTRAAGP DNLAVIAQFV SLLGEVEQKV
      121 IRCFREGGGV PYSEYPRFHK LMAEMSGMVF DAALIDVVLP LVDGLPDRLR SGADVADFGC
      181 GSGRAVKLMA QAFGASRFTG IDFSDEAVAA GTEEAARLGL ANATFERHDL AELDKVGAYD
      241 VITVFDAIHD QAQPARVLQN IYRALRPGGV LLMVDIKASS QLEDNVGVPL STYLYTTSLM
      301 HCMTVSLALD GAGLGTVWGR QLATSMLADA GFTDVTVAEI ESDVLNNYYI ARK
//