LOCUS       SIU00885.1               189 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 Possible
            transcriptional regulatory protein protein.
ACCESSION   LT708304-2299
PROTEIN_ID  SIU00885.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB2274C"
                     /note="Mb2274c, -, len: 189 aa. Equivalent to Rv2250c,
                     len: 189 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (99.5% identity in 189 aa overlap). Possible
                     transcriptional regulatory protein, TetR family. Start
                     unclear; ORF has been shortened since first submission to
                     avoid overlap with Rv2251 (-30 aa). Contains probable
                     helix-turn-helix motif (Score 2243, +6.70 SD) Protein
                     product from Mb2274c detected using SWATH mass
                     spectrometry."
                     /db_xref="GOA:Q7VEN0"
                     /db_xref="InterPro:IPR001647"
                     /db_xref="InterPro:IPR009057"
                     /db_xref="InterPro:IPR023772"
                     /db_xref="InterPro:IPR036271"
                     /db_xref="UniProtKB/Swiss-Prot:Q7VEN0"
BEGIN
        1 MLSMSNDRAD TGGRILRAAA SCVVDYGVDR VTLAEIARRA GVSRPTVYRR WPDTRSIMAS
       61 MLTSHIAAVL REVPLDGDDR EALVKQIVAV ADRLRGDDLI MSVMHSELAR VYITERLGTS
      121 QQVLIEGLAA RLTVAQRSGS VRSGDARRLA TMVLLIAQST IQSADIVDSI LDSAALATEL
      181 THALNGYLC
//