LOCUS SIU00885.1 189 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 Possible transcriptional regulatory protein protein. ACCESSION LT708304-2299 PROTEIN_ID SIU00885.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /locus_tag="BQ2027_MB2274C" /note="Mb2274c, -, len: 189 aa. Equivalent to Rv2250c, len: 189 aa, from Mycobacterium tuberculosis strain H37Rv, (99.5% identity in 189 aa overlap). Possible transcriptional regulatory protein, TetR family. Start unclear; ORF has been shortened since first submission to avoid overlap with Rv2251 (-30 aa). Contains probable helix-turn-helix motif (Score 2243, +6.70 SD) Protein product from Mb2274c detected using SWATH mass spectrometry." /db_xref="GOA:Q7VEN0" /db_xref="InterPro:IPR001647" /db_xref="InterPro:IPR009057" /db_xref="InterPro:IPR023772" /db_xref="InterPro:IPR036271" /db_xref="UniProtKB/Swiss-Prot:Q7VEN0" BEGIN 1 MLSMSNDRAD TGGRILRAAA SCVVDYGVDR VTLAEIARRA GVSRPTVYRR WPDTRSIMAS 61 MLTSHIAAVL REVPLDGDDR EALVKQIVAV ADRLRGDDLI MSVMHSELAR VYITERLGTS 121 QQVLIEGLAA RLTVAQRSGS VRSGDARRLA TMVLLIAQST IQSADIVDSI LDSAALATEL 181 THALNGYLC //